Heparin-induced thrombocytopenia (HIT): Review of incidence, diagnosis, and management

M Hogan, JS Berger - Vascular Medicine, 2020 - journals.sagepub.com
Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening complication of
heparin exposure. Here, we review the pathogenesis, incidence, diagnosis, and …

Polysaccharides from Auricularia auricula: Preparation, structural features and biological activities

N Chen, H Zhang, X Zong, S Li, J Wang, Y Wang… - Carbohydrate …, 2020 - Elsevier
Auricularia auricula is a well-known traditional edible fungus with high nutritional and
pharmacological values. Polysaccharides are identified as one of the pivotal bioactive …

Pathogenesis of heparin-induced thrombocytopenia

GM Arepally, DB Cines - Translational Research, 2020 - Elsevier
There are currently no effective substitutes for high intensity therapy with unfractionated
heparin (UFH) for cardiovascular procedures based on its rapid onset of action, ease of …

Therapeutic plasma exchange and intravenous immune globulin in the treatment of heparin‐induced thrombocytopenia: a systematic review

C Onuoha, KD Barton, ECC Wong, JS Raval… - …, 2020 - Wiley Online Library
Background Immunomodulatory strategies in heparin‐induced thrombocytopenia (HIT)
include the use of intravenous immune globulin (IVIG) and therapeutic plasma exchange …

Mimicking the endothelium: dual action heparinized nitric oxide releasing surface

R Devine, MJ Goudie, P Singha… - … applied materials & …, 2020 - ACS Publications
The management of thrombosis and bacterial infection is critical to ensure the functionality of
medical devices. While administration of anticoagulants is the current antithrombotic clinical …

Enzymatic synthesis of chondroitin sulfate E to attenuate bacteria lipopolysaccharide-induced organ damage

J Li, EM Sparkenbaugh, G Su, F Zhang, Y Xu… - ACS Central …, 2020 - ACS Publications
Chondroitin sulfate E (CS-E) is a sulfated polysaccharide that contains repeating
disaccharides of 4, 6-disulfated N-acetylgalactosamine and glucuronic acid residues. Here …

How can i manage thrombocytopenia in hemodialysis patient? A review

Q Guo, Y Lou, L Liu, P Luo - Therapeutic Apheresis and …, 2020 - Wiley Online Library
Hemodialysis (HD) is the most important treatment for patients with end‐stage renal disease
(ESRD). Thrombocytopenia is a potential treatment complication related to dialysis. Under …

Use of IV immunoglobulin G in heparin-induced thrombocytopenia patients is not associated with increased rates of thrombosis: A population-based study

B Dhakal, L Rein, A Szabo, A Padmanabhan - Chest, 2020 - journal.chestnet.org
Methods Hospital discharges with an ICD-9-CM (The International Classification of
Diseases, Ninth Revision, Clinical Modification) code for HIT (289.84) in the NIS were used …

Perioperative applications of therapeutic plasma exchange in cardiac surgery: a narrative review

A Grazioli, J Athale, K Tanaka, R Madathil… - … of Cardiothoracic and …, 2020 - Elsevier
Therapeutic plasma exchange (TPE) has a number of applications in cardiac surgical
patients and has been used increasingly in high-risk heart and lung transplant patients. In …

[HTML][HTML] Apoptosis signal‐regulating kinase 1 regulates immune‐mediated thrombocytopenia, thrombosis, and systemic shock

P Patel, NF Shaik, Y Zhou, K Golla… - Journal of Thrombosis …, 2020 - Elsevier
Abstract Background Immune complexes (ICs) bind to and activate platelets via FcγRIIA,
causing patients to experience thrombocytopenia, as well as an increased risk of forming …