[HTML][HTML] Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies

JA Grondin, YH Kwon, PM Far, S Haq… - Frontiers in …, 2020 - frontiersin.org
Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

Measuring biological aging in humans: A quest

L Ferrucci, M Gonzalez‐Freire, E Fabbri… - Aging cell, 2020 - Wiley Online Library
The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies

A Cui, H Li, D Wang, J Zhong, Y Chen, H Lu - EClinicalMedicine, 2020 - thelancet.com
Background Knee osteoarthritis (OA) is a major cause of disability in the elderly, however,
there are few studies to estimate the global prevalence, incidence, and risk factors of knee …

Trends in worldwide asthma prevalence

MI Asher, L García-Marcos, NE Pearce… - European …, 2020 - Eur Respiratory Soc
This review of trends in worldwide asthma prevalence starts with defining how asthma
prevalence is measured in populations and how it is analysed. Four population studies of …

The impact of digital technology use on adolescent well-being

T Dienlin, N Johannes - Dialogues in clinical neuroscience, 2020 - Taylor & Francis
This review provides an overview of the literature regarding digital technology use and
adolescent well-being. Overall, findings imply that the general effects are on the negative …

Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications

XR Liu, MM Zhang, ML Gross - Chemical reviews, 2020 - ACS Publications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

Essential role of patient blood management in a pandemic: a call for action

A Shander, SM Goobie, MA Warner… - Anesthesia & …, 2020 - journals.lww.com
Abstract The World Health Organization (WHO) has declared coronavirus disease 2019
(COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 …

Global disability burdens of diabetes-related lower-extremity complications in 1990 and 2016

Y Zhang, PA Lazzarini, SM McPhail… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE No study has reported global disability burden estimates for individual diabetes-
related lower-extremity complications (DRLECs). The Global Burden of Disease (GBD) study …

The excess costs of depression: a systematic review and meta-analysis

H König, HH König, A Konnopka - Epidemiology and psychiatric …, 2020 - cambridge.org
AimsMajor depressive disorders are highly prevalent in the world population, contribute
substantially to the global disease burden and cause high health care expenditures …

Multiplying the efficiency and impact of biofortification through metabolic engineering

D Van Der Straeten, NK Bhullar, H De Steur… - Nature …, 2020 - nature.com
Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal
2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the …