Tryptophan in health and disease

S Comai, A Bertazzo, M Brughera, S Crotti - Advances in clinical chemistry, 2020 - Elsevier
Tryptophan (TRP), an essential amino acid in mammals, is involved in several physiological
processes including neuronal function, immunity, and gut homeostasis. In humans, TRP is …

The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

G Morris, CC Bortolasci, BK Puri, L Olive, W Marx… - Life sciences, 2020 - Elsevier
In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …

[HTML][HTML] Helicobacter pylori infection: Beyond gastric manifestations

MLC Santos, BB de Brito, FAF da Silva… - World journal of …, 2020 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a bacterium that infects more than a half of world's
population. Although it is mainly related to the development of gastroduodenal diseases …

Inflammation, NF-κB, and chronic diseases: how are they linked?

AB Kunnumakkara, B Shabnam, S Girisa… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

Metabolic inflammation—a role for hepatic inflammatory pathways as drivers of comorbidities in nonalcoholic fatty liver disease?

N Gehrke, JM Schattenberg - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a global and growing health concern. Emerging
evidence points toward metabolic inflammation as a key process in the fatty liver that …

Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/-mice

M Kim, A Sahu, Y Hwang, GB Kim, GH Nam, IS Kim… - Biomaterials, 2020 - Elsevier
Unresolved inflammation is a hallmark of many deadly diseases including atherosclerosis, a
silent pathological condition behind majority of cardiovascular diseases. Yet, anti …

[HTML][HTML] Cytokine and chemokine regulation of venous thromboembolism

MY Najem, F Couturaud, CA Lemarié - Journal of Thrombosis and …, 2020 - Elsevier
Morbidity and mortality from venous thromboembolism (VTE), which refers to deep vein
thrombosis and pulmonary embolism, have a substantial effect on the global burden of …

[HTML][HTML] Medicinal plants as a potential and successful treatment option in the context of atherosclerosis

TV Kirichenko, VN Sukhorukov, AM Markin… - Frontiers in …, 2020 - frontiersin.org
Atherosclerosis is a chronic multifactorial disease characterized by mainly changes of blood
lipids profile and inflammation in vessel wall. The cardiovascular disease based on …

Reflections on atherosclerosis: lesson from the past and future research directions

S Minelli, P Minelli, MR Montinari - Journal of multidisciplinary …, 2020 - Taylor & Francis
The clinical manifestations of atherosclerosis are nowadays the main cause of death in
industrialized countries, but atherosclerotic disease was found in humans who lived …

The potential of probiotics in the prevention and treatment of atherosclerosis

VL O'Morain, DP Ramji - Molecular nutrition & food research, 2020 - Wiley Online Library
Atherosclerosis, the underlying cause of cardiovascular diseases such as myocardial
infarction, cerebrovascular accident, and peripheral vascular disease, is the leading cause …