The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2020 - Am Psychiatric Assoc
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

[HTML][HTML] Common and distinct patterns of intrinsic brain activity alterations in major depression and bipolar disorder: voxel-based meta-analysis

J Gong, J Wang, S Qiu, P Chen, Z Luo, J Wang… - Translational …, 2020 - nature.com
Identification of intrinsic brain activity differences and similarities between major depression
(MDD) and bipolar disorder (BD) is necessary. However, results have not yet yielded …

Early childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment

NK Mackes, D Golm, S Sarkar… - Proceedings of the …, 2020 - National Acad Sciences
Early childhood deprivation is associated with higher rates of neurodevelopmental and
mental disorders in adulthood. The impact of childhood deprivation on the adult brain and …

A systematic review of reviews of the outcome of noninstitutional child maltreatment

A Carr, H Duff, F Craddock - Trauma, Violence, & Abuse, 2020 - journals.sagepub.com
The aim of the systematic review described in this article was to synthesize available high-
quality evidence on the outcomes of noninstitutional child maltreatment across the life span …

Abnormalities of intrinsic regional brain activity in first-episode and chronic schizophrenia: a meta-analysis of resting-state functional MRI

J Gong, J Wang, X Luo, G Chen, H Huang… - Journal of psychiatry and …, 2020 - jpn.ca
Background: Resting-state functional MRI (fMRI) studies have provided much evidence for
abnormal intrinsic brain activity in schizophrenia, but results have been inconsistent …

Peer victimization and its impact on adolescent brain development and psychopathology

EB Quinlan, ED Barker, Q Luo, T Banaschewski… - Molecular …, 2020 - nature.com
Chronic peer victimization has long-term impacts on mental health; however, the biological
mediators of this adverse relationship are unknown. We sought to determine whether …

Aberrant structural connectivity in childhood maltreatment: a meta-analysis

L Lim, H Howells, J Radua, K Rubia - Neuroscience & Biobehavioral …, 2020 - Elsevier
We conducted the first meta-analysis of whole-brain voxel-based DTI studies in childhood
maltreatment to elucidate regions of white matter (WM) microstructure abnormality relative to …

Identifying biological markers for improved precision medicine in psychiatry

EB Quinlan, T Banaschewski, GJ Barker… - Molecular …, 2020 - nature.com
Mental disorders represent an increasing personal and financial burden and yet treatment
development has stagnated in recent decades. Current disease classifications do not reflect …

Neural meaning making, prediction, and prefrontal–subcortical development following early adverse caregiving

N Tottenham - Development and psychopathology, 2020 - cambridge.org
Early adversities that are caregiving-related (crEAs) are associated with a significantly
increased risk for mental health problems. Recent neuroscientific advances have revealed …

Childhood maltreatment and cognitive functioning in patients with major depressive disorder: a CAN-BIND-1 report

T Chakrabarty, KL Harkness, SJ McInerney… - Psychological …, 2020 - cambridge.org
BackgroundPatients with major depressive disorder (MDD) display cognitive deficits in
acutely depressed and remitted states. Childhood maltreatment is associated with cognitive …