NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is
activated by various stimuli, transducing a quick but transient transcriptional activity, to …

Gastrointestinal (GI) cancers, especially gastric cancer and colorectal cancer (CRC),
represent a major global health burden. A large population of microorganisms residing in …

Intracellular signalling pathways have provided excellent resource for drug development
particularly in the development of cancer therapeutics. A wide variety of malignancies …

Post-breeding endometritis (ie, inflammation/infection of the endometrium), is a
physiological reaction taking place in the endometrium of mares within 48 h post-breeding …

The nuclear factor kappa B (NF-κB) signaling system, a key regulator of immunologic
processes, also affects a plethora of metabolic changes associated with inflammation and …

With the progress of nanotechnology, the adverse effects of nanoscale materials are
receiving much attention. Inhibition of toll-like receptor 4 (TLR-4)/nuclear factor kappa B (NF …

Hepatic ischemia/reperfusion injury (IRI) is an unavoidable course in liver transplantation,
during which the immune response of inflammation plays a leading part. MicroRNA-450b-5p …

The Physiological functions of IKK-selective substrate identification and their critical roles in
diseases | STEMedicine Skip to main content Skip to main navigation menu Skip to site footer …

Objective Recent studies have shown that tumor-associated macrophages (TAMs) play an
important role in cancer invasion and metastasis. Our previous studies have reported that …

Tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are cytokines that are involved
in the development, proliferation and apoptosis of ovarian follicular cells in domestic …