A neuroscientist's guide to transgenic mice and other genetic tools
The past decade has produced an explosion in the number and variety of genetic tools
available to neuroscientists, resulting in an unprecedented ability to precisely manipulate …
available to neuroscientists, resulting in an unprecedented ability to precisely manipulate …
Chemogenetics a robust approach to pharmacology and gene therapy
O Keifer, K Kambara, A Lau, S Makinson… - Biochemical …, 2020 - Elsevier
Modern developments in organic chemistry, molecular biology, virology, and genetics have
opened new, exciting possibilities to better understand physiology and to create innovative …
opened new, exciting possibilities to better understand physiology and to create innovative …
[HTML][HTML] Nesfatin-1 decreases the motivational and rewarding value of food
Homeostatic and hedonic pathways distinctly interact to control food intake. Dysregulations
of circuitries controlling hedonic feeding may disrupt homeostatic mechanisms and lead to …
of circuitries controlling hedonic feeding may disrupt homeostatic mechanisms and lead to …
Chemogenetic inhibition of dopaminergic projections to the nucleus accumbens has sexually dimorphic effects in the rat gambling task.
TJ Hynes, JMM Ferland, TL Feng… - Behavioral …, 2020 - psycnet.apa.org
Women and men can differ in their propensity to take risks and develop impulse control and
addiction disorders. Sexual dimorphisms in behavioral control by the mesolimbic …
addiction disorders. Sexual dimorphisms in behavioral control by the mesolimbic …
Pituitary adenylate cyclase-activating polypeptide excites proopiomelanocortin neurons: implications for the regulation of energy homeostasis
R Chang, J Hernandez, C Gastelum, K Guadagno… - …, 2020 - karger.com
Objective: We examined whether pituitary adenylate cyclase-activating polypeptide
(PACAP) excites proopiomelanocortin (POMC) neurons via PAC1 receptor mediation and …
(PACAP) excites proopiomelanocortin (POMC) neurons via PAC1 receptor mediation and …
It takes a neural village: Circuit-based approaches for estrogenic regulation of episodic memory
Cognitive behaviors, such as episodic memory formation, are complex processes involving
coordinated activity in multiple brain regions. However, much of the research on hormonal …
coordinated activity in multiple brain regions. However, much of the research on hormonal …
[HTML][HTML] Canine adenovirus 2: A natural choice for brain circuit dissection
A Lavoie, B Liu - Frontiers in Molecular Neuroscience, 2020 - frontiersin.org
Canine adenovirus-2 (CAV) is a canine pathogen that has been used in a variety of
applications, from vaccines against more infectious strains of CAV to treatments for …
applications, from vaccines against more infectious strains of CAV to treatments for …
Gq DREADD activation of CaMKIIa MnPO neurons stimulates nitric oxide activity
AB Marciante, GE Farmer… - Journal of …, 2020 - journals.physiology.org
Designer receptors exclusively activated by designer drugs (DREADDs) modify cellular
activity following administration of the exogenous ligand clozapine-N-oxide (CNO) …
activity following administration of the exogenous ligand clozapine-N-oxide (CNO) …
Combining designer receptors exclusively activated by designer drugs and neuroimaging in experimental models: A powerful approach towards neurotheranostic …
LM Peeters, S Missault, AJ Keliris… - British Journal of …, 2020 - Wiley Online Library
The combination of chemogenetics targeting specific brain cell populations with in vivo
imaging techniques provides scientists with a powerful new tool to study functional neural …
imaging techniques provides scientists with a powerful new tool to study functional neural …
[PDF][PDF] Combining DREADDs and neuroimaging in experimental models: a powerful approach towards neurotheranostic applications
LM Peeters - Unraveling the interplay of brain networks …, 2020 - repository.uantwerpen.be
The combination of chemogenetics targeting specific brain cell populations with invivo
imaging techniques provides scientists with a powerful new tool to study functional neural …
imaging techniques provides scientists with a powerful new tool to study functional neural …