Diagnosis and treatment of Parkinson disease: a review
MJ Armstrong, MS Okun - Jama, 2020 - jamanetwork.com
Importance Parkinson disease is the most common form of parkinsonism, a group of
neurological disorders with Parkinson disease–like movement problems such as rigidity …
neurological disorders with Parkinson disease–like movement problems such as rigidity …
The genetic architecture of Parkinson's disease
Parkinson's disease is a complex neurodegenerative disorder for which both rare and
common genetic variants contribute to disease risk, onset, and progression. Mutations in …
common genetic variants contribute to disease risk, onset, and progression. Mutations in …
[HTML][HTML] In vitro Models of Neurodegenerative Diseases
A Slanzi, G Iannoto, B Rossi, E Zenaro… - Frontiers in cell and …, 2020 - frontiersin.org
Neurodegenerative diseases are progressive degenerative conditions characterized by the
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
[HTML][HTML] The pathology of Parkinson's disease and potential benefit of dietary polyphenols
S Aryal, T Skinner, B Bridges, JT Weber - Molecules, 2020 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized
by a loss of dopaminergic neurons, leading to bradykinesia, rigidity, tremor at rest, and …
by a loss of dopaminergic neurons, leading to bradykinesia, rigidity, tremor at rest, and …
[HTML][HTML] Lipopolysaccharide animal models of Parkinson's disease: Recent progress and relevance to clinical disease
Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders which is characterised neuropathologically by progressive loss of dopaminergic …
disorders which is characterised neuropathologically by progressive loss of dopaminergic …
[HTML][HTML] Behavioral tests in neurotoxin-induced animal models of Parkinson's disease
Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …
[HTML][HTML] Insights into the effects of mesenchymal stem cell-derived secretome in Parkinson's disease
Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …
Neuroinflammatory responses and Parkinson'disease: pathogenic mechanisms and therapeutic targets
L Yang, K Mao, H Yu, J Chen - Journal of Neuroimmune Pharmacology, 2020 - Springer
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disorders of the central nervous system, which mainly impairs the motor system. However …
disorders of the central nervous system, which mainly impairs the motor system. However …
[HTML][HTML] LRRK2 phosphorylation, more than an epiphenomenon
A Marchand, M Drouyer, A Sarchione… - Frontiers in …, 2020 - frontiersin.org
Mutations in the Leucine Rich Repeat Kinase 2 (LRRK2) gene are linked to autosomal
dominant Parkinson's disease (PD), and genetic variations at the LRRK2 locus are …
dominant Parkinson's disease (PD), and genetic variations at the LRRK2 locus are …
[HTML][HTML] Gait progression over 6 years in Parkinson's disease: Effects of age, medication, and pathology
J Wilson, L Alcock, AJ Yarnall, S Lord… - Frontiers in aging …, 2020 - frontiersin.org
Background: Gait disturbance is an early, cardinal feature of Parkinson's disease (PD)
associated with falls and reduced physical activity. Progression of gait impairment in …
associated with falls and reduced physical activity. Progression of gait impairment in …