Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy.
Advancements in technology that enhance our understanding of the biology of the disease …

Although many children and young adults with B-cell acute lymphoblastic leukemia (B-ALL)
are cured with modern, risk-adapted chemotherapy regimens, 10% to 15% of patients will …

Clinical management and risk stratification of B-lymphoblastic leukemia/lymphoma (B-
ALL/LBL) depend largely on identification of chromosomal abnormalities obtained using …

A 6-year-old boy was diagnosed with B-cell acute lymphoblastic leukemia and received
induction chemotherapy on an institutional protocol. Cytogenetic analysis of the leukemic …

Ploidy, besides known translocations in lymphoblasts, is a strong predictor of prognosis in B-
cell progenitor acute lymphoblastic leukemia (BCP-ALL). While hyperdiploidy with> 50 …

Recent genetic studies of pediatric acute lymphoblastic leukemia (ALL), both in B cell
precursor and T cell ALL (B/T-ALL), clarified the landscape of genetic alterations due to …

This chapter covers the most updated classification of neoplastic lymphoid disorders that
affect primarily the lymph nodes and also covers the most updated classification of …

Acute lymphoblastic leukemia (ALL) comprises 75% to 80% of all childhood leukemias. ALL
occurs commonly between 2 and 5 years of age with 80-85% being of B-lineage, T-lineage …

I. 1.1. 1. TGFβ termelése, aktivitása és jelátviteli mechanizmusai 10-I. 1.1. 2 A TGFβ
tumorpromoter és-szuppresszor hatásainak kettőssége 12-I. 1.1. 3. TGFβ érzékenység …

Childhood acute leukemias are genetically complex disorders, with recurrent or random
aberrations found in most patients. Their proper functional characterization is crucial for …