[HTML][HTML] Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
Abstract Calcium (Ca 2+) plays a central role in cardiomyocyte excitation-contraction
coupling. To ensure an optimal electrical impulse propagation and cardiac contraction, Ca …
coupling. To ensure an optimal electrical impulse propagation and cardiac contraction, Ca …
[HTML][HTML] Unbalance between sarcoplasmic reticulum Ca2+ uptake and release: a first step toward Ca2+ triggered arrhythmias and cardiac damage
The present review focusses on the regulation and interplay of cardiac SR Ca 2+ handling
proteins involved in SR Ca 2+ uptake and release, ie, SERCa2/PLN and RyR2. Both RyR2 …
proteins involved in SR Ca 2+ uptake and release, ie, SERCa2/PLN and RyR2. Both RyR2 …
CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts
HT Lu, RQ Feng, JK Tang, JJ Zhou, F Gao… - Cell Death & Disease, 2020 - nature.com
Previous studies indicated that Ca2+/calmodulin-dependent kinase II (CaMKII), a kinase
involved in the modulation of ryanodine receptor activity, activates Ca2+-regulated protease …
involved in the modulation of ryanodine receptor activity, activates Ca2+-regulated protease …
[HTML][HTML] Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury
I Olmedo, G Pino, JA Riquelme, P Aranguiz… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Cardiomyocyte loss is the main cause of myocardial dysfunction following an ischemia-
reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network …
reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network …
Modulation of Ca2+-induced Ca2+ release by ubiquitin protein ligase E3 component n-recognin UBR3 and 6 in cardiac myocytes
XE Ma, B Liu, CX Zhao - Channels, 2020 - Taylor & Francis
ABSTRACT Ca2+-induced Ca2+ release (CICR) from sarcoplasmic reticulum is a finely
tuned process responsible for cardiac excitation and contraction. The ubiquitin–proteasome …
tuned process responsible for cardiac excitation and contraction. The ubiquitin–proteasome …
Úloha beta 1 adrenergních receptorů v srdci chladově adaptovaného potkana
A Liptáková - 2020 - dspace.cuni.cz
V průběhu chladové adaptace dochází k posunu v produkci tepla od třesové termogeneze k
netřesové termogenezi, která je zprostředkována adrenergní signalizací. Bylo též …
netřesové termogenezi, která je zprostředkována adrenergní signalizací. Bylo též …
Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury
I Olmedo Alegría, G Pino Tapia, J Riquelme Meléndez… - 2020 - repositorio.uchile.cl
Cardiomyocyte loss is the main cause of myocardial dysfunction following an ischemia-
reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network …
reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network …
[PDF][PDF] ПРЕДУПРЕЖДЕНИЕ РЕПЕРФУЗИОННОГО ПОВРЕЖДЕНИЯ СЕРДЦА С ПОМОЩЬЮ ДИСТАНТНОГО ПОСТКОНДИЦИОНИРОВАНИЯ И АГОНИСТОВ …
ЛН Маслов, ЮВ Бушов - tnimc.ru
Актуальность исследования. Ишемическое и реперфузионное повреждение сердца
лежит в основе патогенеза острого инфаркта миокарда (ОИМ). В 80-е годы прошлого …
лежит в основе патогенеза острого инфаркта миокарда (ОИМ). В 80-е годы прошлого …
[PDF][PDF] Conditioning Medicine
D Aluja, A Rodriguez-Lopez, M Ruiz-Meana, J Inserte - conditionmed.org
The pathophysiology of reperfusion injury is a complex process that causes cardiomyocyte
death via multiple mechanisms and involves the alteration and interplay of a variety of …
death via multiple mechanisms and involves the alteration and interplay of a variety of …