To better explain daily fluctuations in physical activity and sedentary behavior, investigations
of motivation are turning from social cognitive frameworks to those centered on affect …

Although there is increasing clinical recognition of behavioral addictions, of which gambling
disorder is the prototype example, there is a limited understanding of the psychological …

Abstract Background Substance use disorders (SUDs) are a major public health risk.
However, mechanisms accounting for continued patterns of poor choices in the face of …

Rewarding events enhance memory encoding via dopaminergic influences on hippocampal
plasticity. Phasic dopamine release depends on immediate reward magnitude, but …

Advances in the understanding and management of bipolar disorder (BD) have been slow to
emerge. Despite notable recent developments in neurosciences, our conceptualization of …

When facing decisions to approach rewards or to avoid punishments, we often figuratively
go with our gut, and the impact of metabolic states such as hunger on motivation are well …

The role of the dopamine D2 receptor (D2R) in regulating appetitive behavior continues to
be controversial. Earlier literature suggests that reduced D2R signaling diminishes …

Background Obesity and energy expenditure (EE) are heritable and genetic variants
influencing EE may contribute to the development of obesity. We sought to identify genetic …

Rationale A reduced willingness to perform effort based on the magnitude and probability of
potential rewards has been associated with diminished dopamine function and may be …

Energy expenditure undulates throughout the day and likely motivation for it. The aim of this
investigation was to create a short assessment (CRAVE) to measure transient wants or …