Neural mechanisms underlying the rewarding and therapeutic effects of ketamine as a treatment for alcohol use disorder

CE Strong, M Kabbaj - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
Alcohol use disorder (AUD) is the most prevalent substance use disorder and causes a
significant global burden. Relapse rates remain incredibly high after decades of attempting …

Overlapping projections of neighboring direct and indirect pathway neostriatal neurons to globus pallidus external segment

S Okamoto, J Sohn, T Tanaka, M Takahashi, Y Ishida… - Iscience, 2020 - cell.com
Indirect pathway medium-sized spiny neurons (iMSNs) in the neostriatum are well known to
project to the external segment of the globus pallidus (GPe). Although direct MSNs (dMSNs) …

Chemogenetic selective manipulation of nucleus accumbens medium spiny neurons bidirectionally controls alcohol intake in male and female rats

CE Strong, DP Hagarty, A Brea Guerrero… - Scientific Reports, 2020 - nature.com
The nucleus accumbens (NAc), considered the hub of reward circuitry, is comprised of two
medium spiny neuron (MSN) subtypes that are classified by their enrichment of dopamine 1 …

Vpliv spola na vzdražnost možganske skorje pri Parkinsonovi bolezni in estradiola na učinke levodope na modelu parkinsonizma pri podgani

K Kolmančič - 2020 - repozitorij.uni-lj.si
Demografske in klinične študije kažejo, da so ženske v začetni fazi Parkinsonove bolezni
(PB) bolj zaščitene od moških. Predpostavljali smo, da mora obstajati tudi razlika v …

Mef2c in the development of the striatum

D Quinn - 2020 - orca.cardiff.ac.uk
Understanding the process of normal striatal differentiation is important for gaining insight
into diseases affecting this area of the brain, ranging from addiction to neurodegenerative …

[图书][B] Neural Mechanisms of Alcohol Intake: Ketamine as a Potential Treatment Option

CE Strong - 2020 - search.proquest.com
Alcohol use disorder (AUD) is a chronic relapsing brain disease characterized by
compulsive drinking despite negative consequences. While a majority of the world's …