Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

This review summarizes our current knowledge of primate including human retina focusing
on bipolar, amacrine and ganglion cells and their connectivity. We have two main …

Intracellular calcium (Ca2+) concentration ([Ca2+] i) is a key determinant of cell fate and is
implicated in carcinogenesis. Membrane ion channels are structures through which ions …

Osteoarthritis (OA) is the most common chronic musculoskeletal disorder. It can affect any
joint and is the most frequent single cause of disability in older adults. OA is a progressive …

Background One of the hallmarks of bullous pemphigoid (BP) is moderate to severe chronic
itch. Managing this is difficult because little is known about the mechanisms of itch in BP …

The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …

Mast cells are multifarious immune cells with complex roles in tissue homeostasis and
disease. They produce a plethora of mediators that play roles in inflammation, angiogenesis …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes
coronavirus disease 2019 (COVID-19). SARS-CoV-2 binds the angiotensin-converting …

Substance P (SP) is a tachykinin neuropeptide, implicated in the pathogenesis of various
inflammatory conditions and a critical mediator in pain transmission. Recently, the role of SP …

Depression and pain disorders share a high degree of comorbidity. Inflammatory
mechanisms play an important role in the pathogenesis of depression-chronic somatic pain …