The quest to slow ageing through drug discovery
L Partridge, M Fuentealba, BK Kennedy - Nature Reviews Drug …, 2020 - nature.com
Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
Summary of Updated Recommendations for Primary Prevention of Cardiovascular Disease in Women: JACC State-of-the-Art Review
L Cho, M Davis, I Elgendy, K Epps, KJ Lindley… - Journal of the American …, 2020 - jacc.org
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
women in the United States and worldwide. There has been no American College of …
women in the United States and worldwide. There has been no American College of …
Evidence-based medical management of peripheral artery disease
GH Bevan, KT White Solaru - Arteriosclerosis, thrombosis, and …, 2020 - Am Heart Assoc
Peripheral artery disease is an atherosclerotic disease of the lower extremities associated
with high cardiovascular mortality. Management of this condition may include lifestyle …
with high cardiovascular mortality. Management of this condition may include lifestyle …
Chemoprevention of colorectal cancer
BW Katona, JM Weiss - Gastroenterology, 2020 - Elsevier
Although colorectal cancer (CRC) screening has reduced the incidence of and mortality from
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …
Reverse cardio‐oncology: cancer development in patients with cardiovascular disease
JP Aboumsallem, J Moslehi… - Journal of the American …, 2020 - Am Heart Assoc
Overwhelming epidemiological evidence demonstrate that cardiovascular disease and
cancer represent major health burdens in the United States, and they are the leading causes …
cancer represent major health burdens in the United States, and they are the leading causes …
Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease
D Capodanno, DL Bhatt, JW Eikelboom… - Nature Reviews …, 2020 - nature.com
Advances in antiplatelet therapies for patients with cardiovascular disease have improved
patient outcomes over time, but the challenge of balancing the risks of ischaemia and …
patient outcomes over time, but the challenge of balancing the risks of ischaemia and …
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study
YX Chen, QY Gao, TH Zou, BM Wang… - The Lancet …, 2020 - thelancet.com
Background Chemoprevention of colorectal adenoma and colorectal cancer remains an
important public health goal. The present study aimed to investigate the clinical potential …
important public health goal. The present study aimed to investigate the clinical potential …
Indian guidelines on hypertension-IV (2019)
SN Shah, YP Munjal, SA Kamath, GS Wander… - Journal of Human …, 2020 - nature.com
Hypertension is a major contributor to cardiovascular morbidity and mortality worldwide and
in India. In view of the unique geographical and climatic conditions, ethnic background …
in India. In view of the unique geographical and climatic conditions, ethnic background …
Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options
A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
Abstract Lipoprotein (a)(Lp (a)) was discovered more than 50 years ago, and a decade later,
it was recognized as a risk factor for coronary artery disease. However, it has gained …
it was recognized as a risk factor for coronary artery disease. However, it has gained …
Effect of aspirin vs placebo on the prevention of depression in older people: a randomized clinical trial
Importance Depression is associated with increased inflammation, which may precede its
onset, especially in older people. Some preclinical data suggest potential antidepressant …
onset, especially in older people. Some preclinical data suggest potential antidepressant …