Background Doxorubicin is one of the most commonly prescribed and time-tested anticancer
drugs. Although being considered as a first line drug in different types of cancers, the two …

Glucose, as the main consuming nutrient of the body, faces different destinies in cancer
cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce …

Abstract Lagerstroemia speciosa (L.) Pers.,(Lythraceae) also called Banaba is a native plant
of southeast Asia and is widely used in traditional medicinal system. Herbal tea from banaba …

RAS is the most frequently mutated oncogene in cancer and a critical driver of oncogenesis.
Therapeutic targeting of RAS has been a goal of cancer research for more than 30 years …

The complex pathophysiological mechanisms behind destructive chronic conditions,
including cancer, neurodegenerative diseases, diabetes mellitus, cardiovascular diseases …

Cancer is a devastating disease that has plagued humans from ancient times to this day.
After decades of slow research progress, promising drug development, and the identification …

Abstract Forkhead box O4 (FOXO4) is a member of the FOXO family that regulates a number
of genes involved in metabolism, cell cycle, apoptosis, and cellular homeostasis via …

Forkhead box O transcription factors (FOXOs) regulate several signaling pathways and play
crucial roles in health and disease. FOXOs are key regulators of the expression of genes …

The forkhead box protein O1 (FOXO1) is considered to be a key tumor suppressor due to its
involvement in a broad range of cancer-related functions, including cellular differentiation …

Background Glioblastoma is the most common and deadly form of primary brain cancer,
accounting for more than 13,000 new diagnoses annually in the USA alone. Microglia are …