Association of blood lipids, atherosclerosis and statin use with dementia and cognitive impairment after stroke: a systematic review and meta-analysis

Z Yang, H Wang, D Edwards, C Ding, L Yan… - Ageing research …, 2020 - Elsevier
Background Trial and observational evidence is conflicting in terms of the association of
blood lipids, atherosclerosis and statin use with dementia and cognitive impairment in the …

From beta amyloid to altered proteostasis in Alzheimer's disease

AC Bruni, L Bernardi, C Gabelli - Ageing research reviews, 2020 - Elsevier
Alzheimer's disease (AD) is an age related neurodegenerative disorder causing severe
disability and important socio-economic burden, but with no cure available to date. To …

Cardiovascular health metrics from mid-to late-life and risk of dementia: A population-based cohort study in Finland

Y Liang, T Ngandu, T Laatikainen, H Soininen… - PLoS …, 2020 - journals.plos.org
Background Very few studies have explored the patterns of cardiovascular health (CVH)
metrics in midlife and late life in relation to risk of dementia. We examined the associations …

Predicting cognitive impairment and dementia: A machine learning approach

D Aschwanden, S Aichele, P Ghisletta… - Journal of …, 2020 - content.iospress.com
Background: Efforts to identify important risk factors for cognitive impairment and dementia
have to date mostly relied on meta-analytic strategies. A comprehensive empirical …

Associations between heart failure and risk of dementia: A PRISMA-compliant meta-analysis

J Li, Y Wu, D Zhang, J Nie - Medicine, 2020 - journals.lww.com
Background: There are differences among the outcomes regarding cognitive impairment in
heart failure (HF) because the evidence is fragmented and sample size is small. Therefore …

Sex differences in exercise efficacy: Is midlife a critical window for promoting healthy cognitive aging?

CK Barha, T LiuAmbrose - The FASEB Journal, 2020 - Wiley Online Library
Dementia is one of the most pressing health care issues of this century. As no curative
treatment for dementia exists, research efforts are growing to identify effective lifestyle …

The efficacy of statins in the treatment of Alzheimer's disease: a meta-analysis of randomized controlled trial

K Xuan, T Zhao, G Qu, H Liu, X Chen, Y Sun - Neurological Sciences, 2020 - Springer
Objective Alzheimer's disease (AD) is a common type of dementia, which has caused heavy
global economic and health burden, and the using of statins to treat AD has caused widely …

Incidence of and risk factors for mild cognitive impairment in Chinese older adults with multimorbidity in Hong Kong

Z Xu, D Zhang, RWS Sit, C Wong, JYS Tiu… - Scientific reports, 2020 - nature.com
The aim of our study was to identify the incidence rate of and the risk factors for mild
cognitive impairment (MCI) among Chinese older adults with multimorbidity in primary care …

[HTML][HTML] The cognitive effects of statins are modified by age

AM Alsehli, G Olivo, LE Clemensson, MJ Williams… - Scientific Reports, 2020 - nature.com
To reveal new insights into statin cognitive effects, we performed an observational study on
a population-based sample of 245,731 control and 55,114 statin-taking individuals from the …

Meat consumption in midlife and risk of cognitive impairment in old age: the Singapore Chinese Health Study

YW Jiang, LT Sheng, XF Pan, L Feng, JM Yuan… - European journal of …, 2020 - Springer
Purpose Epidemiological studies directly investigating the association between different
types of meat intake and cognitive impairment are limited. We, therefore, examined this …