[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …
the original concepts and ideas. There is no doubt that nanoformulations are extremely …
Materials for oral delivery of proteins and peptides
TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …
[HTML][HTML] Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors
S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions
Oral delivery of protein drugs is considered a life-changing solution for patients who require
regular needle injections. However, clinical translation of oral protein formulations has been …
regular needle injections. However, clinical translation of oral protein formulations has been …
[HTML][HTML] Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches
In its 33 years, ADDR has published regularly on the po5tential of oral delivery of biologics
especially peptides and proteins. In the intervening period, analysis of the preclinical and …
especially peptides and proteins. In the intervening period, analysis of the preclinical and …
Advances in colon-targeted nano-drug delivery systems: challenges and solutions
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
The influence of nanoparticle properties on oral bioavailability of drugs
Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …
because of its high safety, convenience, lower costs, and high compliance of patients …
Mucus-penetrating particles and the role of ocular mucus as a barrier to micro-and nanosuspensions
A Popov - Journal of Ocular Pharmacology and therapeutics, 2020 - liebertpub.com
The ocular surface is naturally covered with a layer of mucus. Along with other functions, this
mucus layer serves to trap and eliminate foreign substances, such as allergens, pathogens …
mucus layer serves to trap and eliminate foreign substances, such as allergens, pathogens …
[HTML][HTML] Comparing the permeability of human and porcine small intestinal mucus for particle transport studies
The gastrointestinal mucus layer represents the last barrier between ingested food or orally
administered pharmaceuticals and the mucosal epithelium. This complex gel structure plays …
administered pharmaceuticals and the mucosal epithelium. This complex gel structure plays …
Nanoemulsion structure and food matrix determine the gastrointestinal fate and in vivo bioavailability of coenzyme Q10
In this work, we sought to incorporate coenzyme Q10-loaded nanoemulsions into a food
system and to understand the impact of food digestion on the in vivo bioavailability of this …
system and to understand the impact of food digestion on the in vivo bioavailability of this …