Contemporary epidemiology of chronic liver disease and cirrhosis

AM Moon, AG Singal, EB Tapper - Clinical Gastroenterology and …, 2020 - Elsevier
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

[HTML][HTML] Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity

A Lonardo, A Mantovani, S Lugari, G Targher - Annals of hepatology, 2020 - Elsevier
The prevalence of nonalcoholic fatty liver disease (NAFLD) is continuing to rise in many
countries, paralleling the epidemic of obesity worldwide. In the last years, the concept of …

Clinical assessment for high‐risk patients with non‐alcoholic fatty liver disease in primary care and diabetology practices

ZM Younossi, KE Corey, N Alkhouri… - Alimentary …, 2020 - Wiley Online Library
Summary Background Primary care practitioners (PCPs) and diabetologists are at the
frontline of potentially encountering patients with NASH. Identification of those at high risk for …

Mammographic breast density, its changes, and breast cancer risk in premenopausal and postmenopausal women

EY Kim, Y Chang, J Ahn, JS Yun, YL Park, CH Park… - Cancer, 2020 - Wiley Online Library
Background The risk of breast cancer related to changes in breast density over time,
including its regression and persistence, remains controversial. The authors investigated the …

[HTML][HTML] Association between nonalcoholic fatty liver disease and extrahepatic cancers: a systematic review and meta-analysis

SS Liu, XF Ma, J Zhao, SX Du, J Zhang… - Lipids in health and …, 2020 - Springer
Background NAFLD is tightly associated with various diseases such as diabetes,
cardiovascular disease, kidney disease, and cancer. Previous studies had investigated the …

Radix polygoni multiflori and its main component emodin attenuate non-alcoholic fatty liver disease in zebrafish by regulation of AMPK signaling pathway

L Yu, L Gong, C Wang, N Hu, Y Tang… - Drug design …, 2020 - Taylor & Francis
Purpose Nonalcoholic fatty liver disease (NAFLD) has become a predictor of death in many
diseases. This study was carried out to investigate the therapeutic effect of Radix Polygoni …

[HTML][HTML] Relationship between IL-8 circulating levels and TLR2 hepatic expression in women with morbid obesity and nonalcoholic steatohepatitis

T Auguet, L Bertran, J Binetti, C Aguilar… - International journal of …, 2020 - mdpi.com
The progression of nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis
(NASH) is linked to systemic inflammation. Currently, two of the aspects that need further …

[HTML][HTML] MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line

Q Zhang, XF Ma, MZ Dong, J Tan, J Zhang… - Lipids in Health and …, 2020 - Springer
Background MiRNAs are a group of multifunctional non-coding RNAs which play an
important role in the various physiological processes including the development of NAFLD …

[HTML][HTML] Impact of obesity and metabolic health status in the development of non-alcoholic fatty liver disease (NAFLD): A United Kingdom population-based cohort …

A Vusirikala, T Thomas, N Bhala, AA Tahrani… - BMC endocrine …, 2020 - Springer
Background With the obesity epidemic reaching crisis levels, there has been attention
around those who may be resilient to the effects of obesity, termed metabolically healthy …