Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Atherosclerosis can be regarded as chronic inflammatory disease affecting the arterial wall.
Despite the recent progress in studying the pathogenesis of atherosclerosis, some of the …

Nox2 is responsible for artery dysfunction via production of reactive oxidant species. RNA
viruses may activate Nox2, but it is unknown if this occurs in coronavirus 2019 (Covid-19) …

COVID-19 pandemic is posing an unprecedented sanitary threat: antiviral and host-directed
medications to treat the disease are urgently needed. A great effort has been paid to find …

Background Statins are guidelines recommended in patients with peripheral artery disease
(PAD) for the prevention of cardiovascular (CV) events. Comprehensive meta-data on the …

Background. Neurodegenerative diseases (ND) as Alzheimer's disease, Parkinson's
disease, and amyotrophic lateral sclerosis represent a growing cause of disability in the …

Previous studies reported an inverse association between healthy dietary patterns (such as
Mediterranean diet) and the incidence of cardiovascular events. As the mechanism …

Antecedentes y objetivo La pandemia por SARS-CoV-2 condiciona elevadas tasas de
mortalidad en pacientes mayores hospitalizados. Actualmente, pocos estudios incluyen …

It is well established that both an increase in reactive oxygen species (ROS: ie O2•−, H2O2
and OH•), as well as protein aggregation, accompany ageing and proteinopathies such as …

Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic
molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor …