Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities

M Vesterhus, TH Karlsen - Journal of gastroenterology, 2020 - Springer
Primary sclerosing cholangitis (PSC) is a progressive liver disease, histologically
characterized by inflammation and fibrosis of the bile ducts, and clinically leading to multi …

Effect of ursodeoxycholic acid on liver markers: A systematic review and meta‐analysis of randomized placebo‐controlled clinical trials

M Simental‐Mendía, A Sánchez‐García… - British journal of …, 2020 - Wiley Online Library
Aim The objective of this meta‐analysis was to evaluate the effect of ursodeoxycholic acid
(UDCA) therapy on serum liver function tests. Methods PubMed, Web of Science, Scopus …

[HTML][HTML] Adjuvant treatments for biliary atresia

J Burns, M Davenport - Translational pediatrics, 2020 - ncbi.nlm.nih.gov
The treatment of biliary atresia (BA) is predominantly surgical with firstly an attempt at
restoration of bile flow from the native liver by wide excision of the obstructed, obliterated …

[HTML][HTML] The role of complement activation in autoimmune liver disease

M Biewenga, AF Sarasqueta, ME Tushuizen… - Autoimmunity …, 2020 - Elsevier
Introduction The complement system, an essential part of the innate immune system, is
involved in various autoimmune diseases. Activation of the complement system by …

Ursodeoxycholic acid treatment of vanishing bile duct syndromes

C Rust, U Beuers - The Pathophysiology of Biliary Epithelia, 2020 - taylorfrancis.com
Vanishing bile duct syndromes (VBDS) are characterized by progressive destruction of
intrahepatic and sometimes extrahepatic branches of the biliary tree. A common symptom of …

[HTML][HTML] Primary sclerosing cholangitis and primary biliary cirrhosis overlap syndrome: a review

S Mago, GY Wu - Journal of Clinical and Translational Hepatology, 2020 - ncbi.nlm.nih.gov
Primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC) are slow
progressive diseases which have been increasing in prevalence. The pathogeneses of PBC …

Consensus guidelines: best practices for detection, assessment and management of suspected acute drug‐induced liver injury occurring during clinical trials in adults …

M Palmer, A Regev, K Lindor, MI Avigan… - Alimentary …, 2020 - Wiley Online Library
Background Improved knowledge of the molecular pathophysiology and
immunopathogenesis of cholestatic liver diseases in recent years has led to an increased …

The use of biologics in the treatment of autoimmune liver disease

C Chang, A Tanaka, C Bowlus… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Autoimmune liver diseases include autoimmune hepatitis (AIH), primary biliary
cholangitis (PBC), primary sclerosing cholangitis (PSC) and juvenile autoimmune hepatitis …

[HTML][HTML] Урсодезоксихолевая кислота и болезни печени

ГВ Волынец, АИ Хавкин - Лечащий врач, 2020 - cyberleninka.ru
Урсодезоксихолевая кислота (УДХК)-гидрофильная желчная кислота, которая является
мощным антиоксидантом и в настоящее время используется в качестве панацеи для …

[PDF][PDF] Холестатические болезни у детей

ГВ Волынец, АВ Никитин - 2020 - proffopponent.ru
Введение ель монографии—усовершенствовать определение и увеличить
продуктивность терапии холестатических недугов у детей педиатрами, семей ными …