Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

SC Cunnane, E Trushina, C Morland… - Nature reviews Drug …, 2020 - nature.com
The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Coronaviruses pathogenesis, comorbidities and multi-organ damage–A review

K Renu, PL Prasanna, AV Gopalakrishnan - Life sciences, 2020 - Elsevier
Abstract Human coronaviruses, especially COVID-19, is an emerging pandemic infectious
disease with high morbidity and mortality. Coronaviruses are associated with comorbidities …

Behavioral and psychological effects of coronavirus disease-19 quarantine in patients with dementia

A Cagnin, R Di Lorenzo, C Marra, L Bonanni… - Frontiers in …, 2020 - frontiersin.org
Background In March 2020, the World Health Organization declared a global pandemic due
to the novel coronavirus SARS-CoV-2 and several governments planned a national …

World‐Wide FINGERS Network: a global approach to risk reduction and prevention of dementia

M Kivipelto, F Mangialasche, HM Snyder… - Alzheimer's & …, 2020 - Wiley Online Library
Reducing the risk of dementia can halt the worldwide increase of affected people. The
multifactorial and heterogeneous nature of late‐onset dementia, including Alzheimer's …

[HTML][HTML] Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised …

JT Yu, W Xu, CC Tan, S Andrieu, J Suckling… - Journal of Neurology …, 2020 - jnnp.bmj.com
Background Evidence on preventing Alzheimer's disease (AD) is challenging to interpret
due to varying study designs with heterogeneous endpoints and credibility. We completed a …

[HTML][HTML] Physical exercise in the prevention and treatment of Alzheimer's disease

A De la Rosa, G Olaso-Gonzalez… - Journal of sport and …, 2020 - Elsevier
Dementia is one of the greatest global challenges for health and social care in the 21st
century. Alzheimer's disease (AD), the most common type of dementia, is by no means an …

Alzheimer's Disease and Vascular Aging: JACC Focus Seminar

M Cortes-Canteli, C Iadecola - Journal of the American College of …, 2020 - jacc.org
Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia

Z Ismail, SE Black, R Camicioli… - Alzheimer's & …, 2020 - Wiley Online Library
Abstract Since 1989, four Canadian Consensus Conferences on the Diagnosis and
Treatment of Dementia (CCCDTD) have provided evidence‐based dementia guidelines for …

Multidomain interventions to prevent cognitive impairment, Alzheimer's disease, and dementia: From FINGER to World-Wide FINGERS

A Rosenberg, F Mangialasche, T Ngandu… - The journal of …, 2020 - Springer
Alzheimer's disease (AD) and dementia are a global public health priority, and prevention
has been highlighted as a pivotal component in managing the dementia epidemic …

Heart disease and stroke statistics—2020 update: a report from the American Heart Association

SS Virani, A Alonso, EJ Benjamin, MS Bittencourt… - Circulation, 2020 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports on the most up-to-date statistics related to heart disease, stroke …