Dystrophic microglia in late‐onset Alzheimer's disease
WJ Streit, H Khoshbouei, I Bechmann - Glia, 2020 - Wiley Online Library
Here, we summarize current understanding of functional involvement of microglial cells in
the most common neurodegenerative disease to affect humans, which is sporadic or late …
the most common neurodegenerative disease to affect humans, which is sporadic or late …
[HTML][HTML] Distinction of microglia and macrophages in glioblastoma: close relatives, different tasks?
S Brandenburg, A Blank, AD Bungert… - International Journal of …, 2020 - mdpi.com
For decades, it has been known that the tumor microenvironment is significant for glioma
progression, namely the infiltration of myeloid cells like microglia and macrophages. Hence …
progression, namely the infiltration of myeloid cells like microglia and macrophages. Hence …
[HTML][HTML] Efficient strategies for microglia replacement in the central nervous system
Z Xu, Y Rao, Y Huang, T Zhou, R Feng, S Xiong… - Cell reports, 2020 - cell.com
Microglia are important immune cells in the central nervous system (CNS). Dysfunctions of
gene-deficient microglia contribute to the development and progression of multiple CNS …
gene-deficient microglia contribute to the development and progression of multiple CNS …
Systemic inflammation response index predicts survival outcomes in glioblastoma multiforme patients treated with standard stupp protocol
E Topkan, A Kucuk, Y Ozdemir… - Journal of …, 2020 - Wiley Online Library
Objectives. We endeavored to retrospectively assess the prognostic merit of pretreatment
systemic immune response index (SIRI) in glioblastoma multiforme (GBM) patients who …
systemic immune response index (SIRI) in glioblastoma multiforme (GBM) patients who …
Brain parenchymal and extraparenchymal macrophages in development, homeostasis, and disease
Microglia are parenchymal macrophages of the CNS; as professional phagocytes they are
important for maintenance of the brain's physiology. These cells are generated through …
important for maintenance of the brain's physiology. These cells are generated through …
The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy
N Hamilton, HA Rutherford, JJ Petts, HM Isles, T Weber… - Glia, 2020 - Wiley Online Library
The contribution of microglia in neurological disorders is emerging as a leading disease
driver rather than a consequence of pathology. RNAseT2‐deficient leukoencephalopathy is …
driver rather than a consequence of pathology. RNAseT2‐deficient leukoencephalopathy is …
[HTML][HTML] Microglial phenotypes and their relationship to the cannabinoid system: therapeutic implications for Parkinson's disease
Parkinson's disease is a neurodegenerative disorder, the motor symptoms of which are
associated classically with Lewy body formation and nigrostriatal degeneration …
associated classically with Lewy body formation and nigrostriatal degeneration …
Neuroimmune interaction in seizures and epilepsy: focusing on monocyte infiltration
Epilepsy is a major neurological condition that affects millions of people globally. While a
number of interventions have been developed to mitigate this condition, a significant number …
number of interventions have been developed to mitigate this condition, a significant number …
Reactive gliosis contributes to Nrf2-dependent neuroprotection by pretreatment with dimethyl fumarate or Korean red ginseng against hypoxic-ischemia: Focus on …
L Liu, MK Vollmer, MG Kelly, VM Fernandez… - Molecular …, 2020 - Springer
Recently, dimethyl fumarate (DMF) and Korean red ginseng (ginseng), based on their
purported antioxidative and anti-inflammatory properties, have exhibited protective potential …
purported antioxidative and anti-inflammatory properties, have exhibited protective potential …
[HTML][HTML] Regulatory roles of bone in neurodegenerative diseases
Z Yu, Z Ling, L Lu, J Zhao, X Chen, P Xu… - Frontiers in Aging …, 2020 - frontiersin.org
Osteoporosis and neurodegenerative diseases are two kinds of common disorders of the
elderly, which often co-occur. Previous studies have shown the skeletal and central nervous …
elderly, which often co-occur. Previous studies have shown the skeletal and central nervous …