Emergence and significance of carbohydrate-specific antibodies
K Kappler, T Hennet - Genes & Immunity, 2020 - nature.com
Carbohydrate-specific antibodies are widespread among all classes of immunoglobulins.
Despite their broad occurrence, little is known about their formation and biological …
Despite their broad occurrence, little is known about their formation and biological …
DNA-based microarray studies in visceral leishmaniasis: identification of biomarkers for diagnostic, prognostic and drug target for treatment
Visceral leishmaniasis (VL) is one of the major infectious diseases affecting the poorest
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …
Synthetic carbohydrate chemistry and translational medicine
SS Shivatare, CH Wong - The Journal of organic chemistry, 2020 - ACS Publications
The importance of post-translational glycosylation in protein structure and function has
gained significant clinical relevance recently. The latest developments in glycobiology …
gained significant clinical relevance recently. The latest developments in glycobiology …
Antibodies, binding fragments, and methods of use
NH Lin, CC Huang, CY Chen, CHU Kuo-Ching… - US Patent …, 2020 - Google Patents
2017-09-11 Assigned to OBI PHARMA INC. reassignment OBI PHARMA INC. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LIN, NAN …
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LIN, NAN …
Synthesis, Molecular Docking, and Preliminary Evaluation of 2‐(1, 2, 3‐Triazoyl) benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease
GP Costa, RSM Baldinotti, MG Fronza… - …, 2020 - Wiley Online Library
We described here our results on the use of thiourea as a ligand in the copper catalysed
azide‐alkyne cycloaddition (CuAAC) of 2‐azidobenzaldehyde with alkynes. Reactions were …
azide‐alkyne cycloaddition (CuAAC) of 2‐azidobenzaldehyde with alkynes. Reactions were …
Preparation and uses of chlorinated glycerol derivatives
A Canela-Xandri, M Balcells, G Villorbina, P Christou… - Molecules, 2020 - mdpi.com
Crude glycerol (C3H8O3) is a major by-product of biodiesel production from vegetable oils
and animal fats. The increased biodiesel production in the last two decades has forced …
and animal fats. The increased biodiesel production in the last two decades has forced …
Hydrogen-bond-mediated aglycone delivery (HAD) and related methods in carbohydrate chemistry
MP Mannino, AV Demchenko - 2020 - books.rsc.org
The stereocontrol of glycosylation reactions is a constant struggle in the field of synthetic
carbohydrate chemistry. The application of the picoloyl (Pico) substituent can offer numerous …
carbohydrate chemistry. The application of the picoloyl (Pico) substituent can offer numerous …
Anti-HER2 glycoantibodies and uses thereof
CH Wong, CY Wu - US Patent 10,618,973, 2020 - Google Patents
4,137.230 A 1/1979 Hashimoto et al. the ikMkk antibodies that have not 4,151,042 A 4/1979
Higashide et al. een glycoengıneered. 4.248. 870 A 2/1981 Miyashita et al. 4,256,746 A …
Higashide et al. een glycoengıneered. 4.248. 870 A 2/1981 Miyashita et al. 4,256,746 A …
Label-Free Biosensors for Studying Carbohydrate-Protein Interaction
Carbohydrate-protein interactions are omnipresent in nature controlling critical functions of
cell proliferation, cell adhesion, and cell migration in the human body. However, the detailed …
cell proliferation, cell adhesion, and cell migration in the human body. However, the detailed …
Functionalized CARB Pharmacophore (FCP) approach to thio and unsaturated carbohydrate scaffolds with potential anticancer activity
ZJ Witczak, R Bielski, T Poplawski - 2020 - books.rsc.org
This brief review discusses some new developments in the functionalized carb
pharmacophore (FCP) concept introduced by us in 2014. While the examples concentrate …
pharmacophore (FCP) concept introduced by us in 2014. While the examples concentrate …