Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms
The serum level of iron in humans is tightly controlled by the action of the hormone hepcidin
on the iron efflux transporter ferroportin. Hepcidin regulates iron absorption and recycling by …
on the iron efflux transporter ferroportin. Hepcidin regulates iron absorption and recycling by …
Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein
The glycoproteins of hepatitis C virus, E1E2, are unlike any other viral fusion machinery yet
described, and are the current focus of immunogen design in HCV vaccine development; …
described, and are the current focus of immunogen design in HCV vaccine development; …
Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential …
Hepatitis C virus (HCV) infection with associated chronic liver diseases is a major health
problem worldwide. Here, we designed hepatitis B virus (HBV) small surface antigen …
problem worldwide. Here, we designed hepatitis B virus (HBV) small surface antigen …
Evaluation of a series of lipidated tucaresol adjuvants in a Hepatitis C virus vaccine model
TF Belz, ME Olson, E Giang, M Law… - ACS Medicinal …, 2020 - ACS Publications
Hepatitis C virus (HCV) infections represent a global health challenge; however, developing
a vaccine for treatment of HCV infection has remained difficult as heterogeneous HCV …
a vaccine for treatment of HCV infection has remained difficult as heterogeneous HCV …
Structure of human ferroportin reveals molecular basis of iron homeostasis
The serum iron level in humans is tightly controlled by the action of the hormone hepcidin on
the iron efflux transporter ferroportin. Hepcidin negatively regulates iron absorption and iron …
the iron efflux transporter ferroportin. Hepcidin negatively regulates iron absorption and iron …
Structure of human ferroportin bound to hepcidin reveals mechanisms of iron homeostasis
The serum iron level in humans is tightly controlled by the action of the hormone hepcidin on
the iron efflux transporter ferroportin. Hepcidin negatively regulates iron absorption and …
the iron efflux transporter ferroportin. Hepcidin negatively regulates iron absorption and …