[HTML][HTML] Continuous flow synthesis of heterocycles: A recent update on the flow synthesis of indoles

M Colella, L Degennaro, R Luisi - Molecules, 2020 - mdpi.com
Indole derivatives are among the most useful and interesting heterocycles employed in drug
discovery and medicinal chemistry. In addition, flow chemistry and flow technology are …

A Set of phenyl sulfonate metal coordination complexes triggered Biginelli reaction for the high efficient synthesis of 3,4‐dihydropyrimidin‐2(1H)‐ones under solvent …

YT Wang, GM Tang, YS Wu - Applied Organometallic …, 2020 - Wiley Online Library
Three new metal coordination complexes, namely,[Co (DPE)(H2O) 4](DPE)(BS) 2 (1),[Co
(DPE) 2 (H2O) 4](ABS) 2 (2),[Co (DPE)(H2O) 4](MBS) 2 (CH3OH) 2 (3)[DPE=(E)‐1, 2‐di …

Green enabling technologies for competitive synthesis of pharmaceutical lead compounds

S Tagliapietra, A Binello, F Bucciol… - Current …, 2020 - ingentaconnect.com
Combinations of different technologies are at the heart of the development and
implementation of new, innovative processes and approaches for Industry 4.0 in the field of …

Three-component spiropyran synthesis via tandem alkylation-condensation

H Swinson, A Perry - Tetrahedron, 2020 - Elsevier
A catalyst-free, three-component alkylation-condensation cascade for spiropyran synthesis
has been developed, using readily available building blocks (indoles, alkyl halides …

Development of large-scale oxidative Bromination with HBr-DMSO by using a continuous-flow microwave system for the subsequent synthesis of 4-Methoxy-2 …

Y Jin, J Yang, X Feng, J Li, J Xu, X Chen… - Journal of Flow …, 2020 - Springer
An efficient procedure of continuous-flow microwave reactor, for oxidative bromination with
HBr (hydrogen bromide)-DMSO (dimethyl sulphoxide) in large scale is described herein …

8‐Prenylflavanones through Microwave Promoted Tandem Claisen Rearrangement/6‐endo‐trig Cyclization and Cross Metathesis

C Schultze, S Foß, B Schmidt - European Journal of Organic …, 2020 - Wiley Online Library
Prenylated flavanones were obtained from ortho‐allyloxy chalcones through a one‐pot
sequence of Claisen rearrangement and 6‐endo‐trig cyclization, followed by olefin cross …

Microwave flow chemistry

JP Barham, E Koyama, Y Norikane… - RF Power Semiconductor …, 2020 - Springer
This chapter presents examples of and advocates for the adoption of tunable solid-state
(semiconductor) oscillator single-mode microwave flow reactors toward laboratory and …

Reaktoren für spezielle technisch-chemische Prozesse: Mikrowellenreaktoren

A Stadler, A Härter - … , Chemische Reaktionsapparate in Theorie und Praxis, 2020 - Springer
Das Kapitel beschreibt nach einem kurzen historischen Abriss die Technologie und die
Vorteile moderner Mikrowellenreaktoren für die chemische Synthese. Nach kompakter …