Stimuli‐responsive biomolecule‐based hydrogels and their applications

M Vázquez‐González, I Willner - … Chemie International Edition, 2020 - Wiley Online Library
This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and
proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with …

pH-sensitive biomaterials for drug delivery

S Zhuo, F Zhang, J Yu, X Zhang, G Yang, X Liu - Molecules, 2020 - mdpi.com
The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …

Smart injectable hydrogels for cancer immunotherapy

Y Chao, Q Chen, Z Liu - Advanced Functional Materials, 2020 - Wiley Online Library
Hydrogels, a class of materials with a 3D network structure, are widely used in various fields
especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and …

miR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration

H Hu, L Dong, Z Bu, Y Shen, J Luo… - Journal of …, 2020 - Taylor & Francis
Articular cartilage has limited self-regenerative capacity and the therapeutic methods for
cartilage defects are still dissatisfactory in clinic. Recent studies showed that exosomes …

Nanoparticle–hydrogel superstructures for biomedical applications

Y Jiang, N Krishnan, J Heo, RH Fang… - Journal of Controlled …, 2020 - Elsevier
The incorporation of nanoparticles into hydrogels yields novel superstructures that have
become increasingly popular in biomedical research. Each component of these nanoparticle …

Healthcare applications of pH-sensitive hydrogel-based devices: a review

A Hendi, M Umair Hassan, M Elsherif… - International journal …, 2020 - Taylor & Francis
Abstract pH-sensitive hydrogels have been developed greatly over the past few years. This
has been possible due to the synthesis of new hydrogel systems with increased sensitivity–a …

Fabrication of versatile dynamic hyaluronic acid-based hydrogels

W Shi, B Hass, MA Kuss, H Zhang, S Ryu, D Zhang… - Carbohydrate …, 2020 - Elsevier
In this study, an injectable and self-healing hydrogel based on the boronic ester dynamic
covalent bond between phenylboronic acid modified hyaluronic acid (HA-PBA) and the …

Composite Hydrogels in Three-Dimensional in vitro Models

Z Zhao, C Vizetto-Duarte, ZK Moay… - … in Bioengineering and …, 2020 - frontiersin.org
3-dimensional (3D) in vitro models were developed in order to mimic the complexity of real
organ/tissue in a dish. They offer new possibilities to model biological processes in more …

Nanoparticle-loaded hydrogel for the light-activated release and photothermal enhancement of antimicrobial peptides

SCT Moorcroft, L Roach, DG Jayne… - … applied materials & …, 2020 - ACS Publications
Rising concerns over multidrug-resistant bacteria have necessitated an expansion to the
current antimicrobial arsenal and forced the development of novel delivery strategies that …

Immunomodulation of MSCs and MSC-derived extracellular vesicles in osteoarthritis

X Zhao, Y Zhao, X Sun, Y Xing, X Wang… - … in Bioengineering and …, 2020 - frontiersin.org
Osteoarthritis (OA) has become recognized as a low-grade inflammatory state. Inflammatory
infiltration of the synovium by macrophages, T cells, B cells, and other immune cells is often …