Epigenomic dysregulation in schizophrenia: in search of disease etiology and biomarkers
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …
that causes very significant disability in young people. While schizophrenia has a strong …
Behavior-related gene regulatory networks: A new level of organization in the brain
Neuronal networks are the standard heuristic model today for describing brain activity
associated with animal behavior. Recent studies have revealed an extensive role for a …
associated with animal behavior. Recent studies have revealed an extensive role for a …
Reverse-genetics studies of lncRNAs—what we have learnt and paths forward
F Gao, Y Cai, P Kapranov, D Xu - Genome biology, 2020 - Springer
Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
Psychiatric disorders and lncRNAs: a synaptic match
Psychiatric disorders represent a heterogeneous class of multifactorial mental diseases
whose origin entails a pathogenic integration of genetic and environmental influences …
whose origin entails a pathogenic integration of genetic and environmental influences …
Role of long noncoding RNA Gas5 in cocaine action
Abstract Background Long noncoding RNAs (lncRNAs) are a class of transcribed RNA
molecules greater than 200 nucleotides in length. Although lncRNAs do not encode …
molecules greater than 200 nucleotides in length. Although lncRNAs do not encode …
The potential role of epigenetic drugs in the treatment of anxiety disorders
J Peedicayil - Neuropsychiatric Disease and Treatment, 2020 - Taylor & Francis
There is increasing evidence that abnormalities in epigenetic mechanisms of gene
expression contribute to the pathogenesis of anxiety disorders (ADs). This article discusses …
expression contribute to the pathogenesis of anxiety disorders (ADs). This article discusses …
Long noncoding RNA PAHAL modulates locust behavioural plasticity through the feedback regulation of dopamine biosynthesis
X Zhang, Y Xu, B Chen, L Kang - PLoS Genetics, 2020 - journals.plos.org
Some long noncoding RNAs (lncRNAs) are specifically expressed in brain cells, implying
their neural and behavioural functions. However, how lncRNAs contribute to neural …
their neural and behavioural functions. However, how lncRNAs contribute to neural …
The genetic landscape of crystallins in congenital cataract
Background The crystalline lens is mainly composed of a large family of soluble proteins
called the crystallins, which are responsible for its development, growth, transparency and …
called the crystallins, which are responsible for its development, growth, transparency and …
Long non-coding RNA derived from lncRNA–mRNA co-expression networks modulates the locust phase change
Long non-coding RNAs (lncRNAs) regulate various biological processes ranging from gene
expression to animal behavior. Although protein-coding genes, microRNAs, and …
expression to animal behavior. Although protein-coding genes, microRNAs, and …
Rationale, relevance, and limits of stress-induced psychopathology in rodents as models for psychiatry research: an introductory overview
M Italia, C Forastieri, A Longaretti, E Battaglioli… - International Journal of …, 2020 - mdpi.com
Emotional and cognitive information processing represent higher-order brain functions. They
require coordinated interaction of specialized brain areas via a complex spatial and …
require coordinated interaction of specialized brain areas via a complex spatial and …