Elevated levels of reactive oxygen species (ROS) have commonly been implicated in a
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …

Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …

In this perspective, we discuss iron-complexes as drug candidates that are promising
alternatives to conventional platinum-based chemotherapies owing to their broad range of …

Nanocarriers are employed to deliver photosensitizers for photodynamic therapy (PDT)
through the enhanced penetration and retention effect, but disadvantages including the …

Boronic acid (and ester) prodrugs targeting the overexpressed level of reactive oxygen
species within tumor microenvironment represent a promising area for the discovery of new …

Most cancer chemotherapy regimens rely on the use of two or more chemotherapeutic
agents. However, achieving the best possible dosing of the individual drugs can be …

Reactive oxygen species (ROS)-responsive nanomedicine has been extensively developed
to improve the therapeutic effects while reducing the systemic toxicity. ROS, as important …

Hypothermal photothermal therapy (HPTT) employs hyperthermia (< 45° C) to destroy tumor
cells with negligible side effects to the surrounding normal tissues. Despite extensive …

Reported is the FeIII‐activated lysosome‐targeting prodrug FerriIridium for gastric cancer
theranostics. It contains a meta‐imino catechol group that can selectively bond to, and be …

Six N-phenylcarbazole/triphenylamine modified half-sandwiched iridium (III) Schiff base
compounds ([(η5-Cpx) Ir (N^ N) Cl] PF6) were synthesised and characterised in this study …