Genomics of periodontal disease and tooth morbidity

T Morelli, CS Agler, K Divaris - Periodontology 2000, 2020 - Wiley Online Library
In this review we critically summarize the evidence base and the progress to date regarding
the genomic basis of periodontal disease and tooth morbidity (ie, dental caries and tooth …

[HTML][HTML] Genetic networks in Parkinson's and Alzheimer's disease

J Kelly, R Moyeed, C Carroll, S Luo, X Li - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common
neurodegenerative diseases and there is increasing evidence that they share common …

[HTML][HTML] Qtlizer: comprehensive QTL annotation of GWAS results

M Munz, I Wohlers, E Simon, T Reinberger, H Busch… - Scientific Reports, 2020 - nature.com
Exploration of genetic variant-to-gene relationships by quantitative trait loci such as
expression QTLs is a frequently used tool in genome-wide association studies. However, the …

High carbohydrate and noodle/meat-rich dietary patterns interact with the minor haplotype in the 22q13 loci to increase its association with non-alcoholic fatty liver …

S Park, S Kang - Nutrition Research, 2020 - Elsevier
Non-alcoholic fatty liver (NAFLD) is prevalent in Asians despite the low obesity rate. We
hypothesized that the haplotype of genetic variants in the 22q13 loci has a strong …

[HTML][HTML] Identification of key genes associated with multiple sclerosis based on gene expression data from peripheral blood mononuclear cells

Z Shang, W Sun, M Zhang, L Xu, X Jia, R Zhang, S Fu - PeerJ, 2020 - peerj.com
The aim of this study was to identify the potential key candidate genes of multiple sclerosis
(MS) and uncover mechanisms in MS. We combined data from the microarray expression …

Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis

H Zhang, L Liu, JJ Ni, XT Wei, GJ Feng, XL Yang… - Osteoporosis …, 2020 - Springer
Aiming to identify pleiotropic genomic loci for bone mineral density and bone size, we
performed a bivariate GWAS in five discovery samples and replicated in two large-scale …

[PDF][PDF] VU Research Portal

M Punt, M Nematimoez, JH van Dieën… - Journal of …, 2020 - research.vu.nl
Abstract The Last Interglaciation (∼ 130 to 116 ka) is a time period with a strong
astronomicallyinduced seasonal forcing of insolation compared to modern. Proxy records …