A review of micronutrients and the immune system–working in harmony to reduce the risk of infection

AF Gombart, A Pierre, S Maggini - Nutrients, 2020 - mdpi.com
Immune support by micronutrients is historically based on vitamin C deficiency and
supplementation in scurvy in early times. It has since been established that the complex …

B vitamins and one-carbon metabolism: implications in human health and disease

P Lyon, V Strippoli, B Fang, L Cimmino - Nutrients, 2020 - mdpi.com
Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …

[HTML][HTML] Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop

P Maruvada, PJ Stover, JB Mason, RL Bailey… - The American journal of …, 2020 - Elsevier
Folate, an essential nutrient found naturally in foods in a reduced form, is present in dietary
supplements and fortified foods in an oxidized synthetic form (folic acid). There is …

Current state of evidence: influence of nutritional and nutrigenetic factors on immunity in the COVID-19 pandemic framework

S Galmés, F Serra, A Palou - Nutrients, 2020 - mdpi.com
The pandemic caused by the new coronavirus has caused shock waves in many countries,
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …

[HTML][HTML] Importance of dietary changes during the coronavirus pandemic: how to upgrade your immune response

A Chaari, G Bendriss, D Zakaria… - Frontiers in Public …, 2020 - frontiersin.org
The new coronavirus pandemic continues to spread causing further public health, social,
and economic issues. The disparities in the rates of death between countries poses …

Folic acid versus 5-methyl tetrahydrofolate supplementation in pregnancy

E Ferrazzi, G Tiso, D Di Martino - … Journal of Obstetrics & Gynecology and …, 2020 - Elsevier
Folate (vitamin B9) is widely accepted to protect against fetal neural tube defects. The main
sources of dietary folate are folic acid-fortified foods and folic acid-containing dietary …

Vitamin supplements in the Era of SARS-Cov2 pandemic

CA Michele, B Angel, L Valeria… - GSC Biological and …, 2020 - gsconlinepress.com
Recently, the rapid and extensive spread of a novel human RNA betacoronavirus, known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing a worldwide …

Bacterial folate biosynthesis and colorectal cancer risk: more than just a gut feeling

DE Kok, WT Steegenga, EJ Smid… - Critical reviews in …, 2020 - Taylor & Francis
Folate is a B-vitamin with an important role in health and disease. The optimal folate status
with regard to human health remains controversial. A low intake of natural folate as well as …

[HTML][HTML] High-dose folic acid supplementation results in significant accumulation of unmetabolized homocysteine, leading to severe oxidative stress in Caenorhabditis …

K Koseki, Y Maekawa, T Bito, Y Yabuta, F Watanabe - Redox Biology, 2020 - Elsevier
Using Caenorhabditis elegans as a model animal, we evaluated the effects of chronical
supplementation with high-dose folic acid on physiological events such as life cycle and egg …

Effects of MTHFR C677T polymorphism on vitamin D, homocysteine and natural killer cell cytotoxicity in women with recurrent pregnancy losses

K Ota, T Takahashi, A Han, S Damvaeba… - Human …, 2020 - academic.oup.com
SUMMARY ANSWER: Women with MTHFR 677TT (homozygous mutation, TT) genotype
have significantly lower vitamin D levels, higher homocysteine and natural killer (NK) cell …