Abstract Context Atypical femur fractures (AFFs) are serious adverse events associated with
bisphosphonates and often show poor healing. Evidence acquisition We performed a …

Osteoporosis‐related fractures are undertreated, due in part to misinformation about
recommended approaches to patient care and discrepancies among treatment guidelines …

Osteoporosis and resulting osteoporotic fractures are responsible for significant morbidity,
excess mortality, and health care costs in the developed world. Medical therapy for …

Objective A hitherto undescribed phenotype of early onset muscular dystrophy associated
with sensorineural hearing loss and primary ovarian insufficiency was initially identified in 2 …

Asian race, younger age, higher body mass index (BMI) and antiresorptive drugs have all
been associated with atypical femur fractures (AFFs). This increased risk of AFF in Asians is …

Atypical femur fractures (AFFs), considered rare associations of bisphosphonates, have also
been reported in patients with monogenic bone disorders without bisphosphonate use. The …

Although alkaline phosphatase (ALP) activity is relatively low in carriers of recessive type
hypophosphatasia (HPP), most are asymptomatic and therefore do not undergo medical …

Aims The processes linking long-term bisphosphonate treatment to atypical fracture remain
elusive. To establish a means of exploring this link, we have examined how long-term …

Bisphosphonates (BPs) have been in the market for the past 40 years and proven beneficial
especially for patients with osteoporosis and prevention of hypercalcemic in malignancy …

RESUMO Fraturas Femorais Atípicas (FFAs) são descritas como decorridas por trauma
mínimo, na região subtrocantérica ou diafisária do fêmur, frequentemente associadas ao …