Heterotypic cell–cell communication regulates glandular stem cell multipotency

A Centonze, S Lin, E Tika, A Sifrim, M Fioramonti… - Nature, 2020 - nature.com
Glandular epithelia, including the mammary and prostate glands, are composed of basal
cells (BCs) and luminal cells (LCs),. Many glandular epithelia develop from multipotent …

[HTML][HTML] RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development

R Mevel, I Steiner, S Mason, LCA Galbraith, R Patel… - Elife, 2020 - elifesciences.org
The characterization of prostate epithelial hierarchy and lineage heterogeneity is critical to
understand its regenerative properties and malignancies. Here, we report that the …

PROSTATE CARCINOGENESIS: DEPICTING A PROPOSED PATHWAY FOR PROSTATE CANCER PRECURSOR LESION DEVELOPMENT USING 3D ANIMATION

W Guzman - 2020 - jscholarship.library.jhu.edu
Prostate cancer is one of the most common malignant neoplasms among men in Western
countries (De Marzo et al. 2017). In 2020, there will be an estimated 191,930 American men …