Victor McKusick provided the first systematic description of cardiovascular disease in
patients with Marfan syndrome in 1955 (1). Limited life expectancy among affected …

Background Root remodeling is one form of valve-preserving root replacement to treat
patients with aortic regurgitation (AR) and root aneurysm. We have consistently used it for …

• Aortic valve replacement (AVR) has become increasingly safe even though an older
population of patients is now being treated, with the best outcomes achieved at high-volume …

The last decade has seen an increasing awareness for patients with connective disorders
and patients with Marfan syndrome (MFS) in particular. MFS has long been the only …

The approach to systematizing information about the connective tissue dysplasia in Russian
and foreign literature differs. In foreign clinical guidelines and reviews, syndrom forms of …

Back ground Ascending aortic diseases are life-threatening conditions that have an
increasing incidence. The modified Bentall procedure has become the technique of choice …

Background: Ascending aortic involvement in Behçet's disease is very rare, and often
accompanied by aortic root dilatation. In cases with aortic valve insufficiency without valve …