Natural killer (NK) cells play a pivotal role in cancer immunotherapy due to their innate
ability to detect and kill tumorigenic cells. The decision to kill is determined by the …

Major histocompatibility complex class I (MHC-I)-restricted immune responses are largely
attributed to cytotoxic T lymphocytes (CTLs). However, natural killer (NK) cells, as predicted …

In the past decade, the study of NK cells was transformed by the discovery of three ways
these “innate” immune cells display adaptive immune behavior, including the ability to form …

Simple Summary Hematopoietic stem cell transplantation (HSCT) causes early immune
deficiency and susceptibility to both opportunistic infections and cancer relapse. In this …

In Russia, cancer is the second leading cause of death following cardiovascular diseases.
Adoptive transfer of NK cells is a promising approach to fight cancer; however, for their …

Аннотация Одна из самых распространенных причин смертей пациентов в России,
наряду с болезнями системы кровообращения,-это онкологические заболевания …

Vaccinia virus (VACV) is a poxvirus and is the vaccine used to eradicate smallpox. It is also
an expression vector for heterologous antigens and an oncolytic virus for cancer therapy …

Natural killer (NK) cells are cytotoxic innate immune cells that provide protection from
pathogens and tumors. To carry out these functions, NK cells must distinguish between …

Natural killer (NK) cells play a fundamental role in protecting the host against cancerous and
virally infected cells, however the mechanisms that control NK cell maturation and Ly49 …