Identification of 2-((2, 3-dihydrobenzo [b][1, 4] dioxin-6-yl) amino)-N-phenylpropanamides as a novel class of potent DprE1 inhibitors

BC Whitehurst, RJ Young, GA Burley, M Cacho… - Bioorganic & Medicinal …, 2020 - Elsevier
The identification of a novel series of DprE1 inhibitors based on a 2-((2, 3-dihydrobenzo
[b][1, 4] dioxin-6-yl) amino)-N-phenylpropanamide scaffold is described herein. SAR …

Design, synthesis and biological activities of compounds containing 1, 3, 4-oxadiazole or 1, 3, 4-thiadiazole

L Yan, Y Li, M Deng, A Chen… - Chinese Journal of …, 2020 - sioc-journal.cn
有机化学 Page 1 有机化学 Chinese Journal of Organic Chemistry ARTICLE * Corresponding
author. E-mail: huixiong.chen@parisdescartes.fr Received July 30, 2019; revised September …

Design and Generation of Peptidomimetic ClpP Activator and N-Phenyl-1-Naphthylamine Libraries as Tools for Understanding Physicochemical Properties that …

QMR Gibaut - 2020 - shareok.org
Gram-negative bacteria pose a major threat to human health as they demonstrate low
sensitivity to most antibiotics. This lack of sensitivity to antimicrobials is largely due to the …

New Aspects of the Double Interrupted and Vinylogous Nazarov Cyclization

Y Karpov - 2020 - era.library.ualberta.ca
Yury Karpov Page 1 New Aspects of the Double Interrupted and Vinylogous Nazarov Cyclization
by Yury Karpov A thesis submitted in partial fulfillment of the requirements for the degree of …