Pathogenic genome signatures that damage motor neurons in amyotrophic lateral sclerosis

A Yousefian-Jazi, YH Seol, J Kim, HL Ryu, J Lee… - Cells, 2020 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease and a
neurodegenerative disorder, affecting the upper and/or lower motor neurons. Notably, it …

Stathmin-2: adding another piece to the puzzle of TDP-43 proteinopathies and neurodegeneration

JD Glass - The Journal of Clinical Investigation, 2020 - Am Soc Clin Investig
Cytoplasmic aggregated proteins are a common neuropathological feature of
neurodegenerative diseases. Cytoplasmic mislocalization and aggregation of TAR-DNA …