Highlights•Zebrafish are a useful tool for screening new drugs for inflammation.•This teleost
shares several inflammatory mediators and receptors with mammals.•The real-time …

Cancer frequency and prevalence have been increasing in the past decades, with
devastating impacts on patients and their families. Despite the great advances in targeted …

Aims A robust inflammatory response to tissue injury is a necessary part of the repair
process but the deposition of scar tissue is a direct downstream consequence of this …

Single-nucleotide polymorphisms in the gene encoding G protein-coupled receptor 35
(GPR35) are associated with increased risk of inflammatory bowel disease. However, the …

Despite the common knowledge that the reticuloendothelial system is largely responsible for
blood clearance of systemically administered nanoparticles, the sequestration mechanism …

Short-chain fatty acids (SCFAs) are produced by microbial fermentation of dietary fiber in the
gut. Butyrate is a particularly important SCFA with anti-inflammatory properties and is …

Tissue damage triggers a rapid and robust inflammatory response in order to clear and
repair a wound. Remarkably, many of the cell biology features that underlie the ability of …

The specific roles of the two major innate immune cell types–neutrophils and macrophages–
in response to infection and sterile inflammation are areas of great interest. The larval …

Mucosal surfaces such as fish gills interface between the organism and the external
environment and as such are major sites of foreign Ag encounter. In the gills, the balance …

Currently, there is no treatment for recovery of human nerve function after damage to the
central nervous system (CNS), and there are limited regenerative capabilities in the …