Recent understanding of soil acidobacteria and their ecological significance: a critical review

S Kalam, A Basu, I Ahmad, RZ Sayyed… - Frontiers in …, 2020 - frontiersin.org
Acidobacteria represents an underrepresented soil bacterial phylum whose members are
pervasive and copiously distributed across nearly all ecosystems. Acidobacterial sequences …

[HTML][HTML] Molecular and biotechnological aspects of secondary metabolites in actinobacteria

R Salwan, V Sharma - Microbiological research, 2020 - Elsevier
The ability to produce plethora of secondary metabolites and enzymes for pharmaceutical,
agricultural and biotechnological applications make actinobacteria one of the most explored …

Microbial siderophore–A boon to agricultural sciences

SK Ghosh, T Bera, AM Chakrabarty - Biological Control, 2020 - Elsevier
Application of microbes or their products in our life is increasing as research on microbiology
is proceeding. Many scientists are now paying much interest on research and proper …

Iron metabolism at the interface between host and pathogen: from nutritional immunity to antibacterial development

M Marchetti, O De Bei, S Bettati, B Campanini… - International journal of …, 2020 - mdpi.com
Nutritional immunity is a form of innate immunity widespread in both vertebrates and
invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit …

Comparative Genomics of Microbacterium Species to Reveal Diversity, Potential for Secondary Metabolites and Heavy Metal Resistance

E Corretto, L Antonielli, A Sessitsch, C Höfer… - Frontiers in …, 2020 - frontiersin.org
Microbacterium species have been isolated from a wide range of hosts and environments,
including heavy metal-contaminated sites. Here, we present a comprehensive analysis on …

Microbial Engineering for Production of N‐Functionalized Amino Acids and Amines

M Mindt, T Walter, P Kugler… - Biotechnology …, 2020 - Wiley Online Library
N‐functionalized amines play important roles in nature and occur, for example, in the
antibiotic vancomycin, the immunosuppressant cyclosporine, the cytostatic actinomycin, the …

Puffer fish gut microbiota studies revealed unique bacterial co-occurrence patterns and new insights on tetrodotoxin producers

Z Li, J Tian, Y Lai, CH Lee, Z Cai, CF Yu - Marine drugs, 2020 - mdpi.com
Tetrodotoxin (TTX) is a potent neurotoxin isolated mainly from toxic puffer fish. To date, the
TTX biosynthetic mechanism inside its hosts remains unresolved. Here, we hypothesize the …

Genome mining and biosynthesis of primary amine-acylated desferrioxamines in a marine gliding bacterium

ZJ Wang, H Zhou, G Zhong, L Huo, YJ Tang… - Organic …, 2020 - ACS Publications
Genome mining of Fulvivirga sp. W222 revealed a desferrioxamine-like biosynthetic gene
cluster containing an unknown gene fulF that is conserved in many Bacteroidetes species. A …

Generation of fluorinated amychelin siderophores against Pseudomonas aeruginosa infections by a combination of genome mining and mutasynthesis

F Xie, S Dai, Y Zhao, P Huang, S Yu, B Ren… - Cell Chemical …, 2020 - cell.com
Pioneering microbial genomic surveys have revealed numerous untapped biosynthetic
gene clusters, unveiling the great potential of new natural products. Here, using a …

The siderophore synthetase IucA of the aerobactin biosynthetic pathway uses an ordered mechanism

LS Mydy, DC Bailey, KD Patel, MR Rice, AM Gulick - Biochemistry, 2020 - ACS Publications
Biosynthesis of the hydroxamate siderophore aerobactin requires the activity of four proteins
encoded within the iuc operon. Recently, we biochemically reconstituted the biosynthetic …