Chronic-diabetes-related complications simultaneously compromise both the micro-and
macrovascular trees, with target organs considered as the paradigm of large vessel injury …

Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique
that has been increasingly used to image the retinal vasculature at capillary level resolution …

The essential function of the circulatory system is to continuously and efficiently supply the
O2 and nutrients necessary to meet the metabolic demands of every cell in the body, a …

The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …

Retinal remodeling is a progressive series of negative plasticity revisions that arise from
retinal degeneration, and are seen in retinitis pigmentosa, age-related macular …

Background/aims As a protrusion from the brain, the retina might reflect the status of the
brain. Previous studies showed a decrease in vessel density and foveal avascular zone …

Background Optical coherence tomography angiography (OCT-A) has emerged as a novel,
fast, safe and non-invasive imaging technique of analyzing the retinal and choroidal …

Adequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood
and blood flow to the tissue. Oximetry is a technique for the assessment of blood …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …