There and back again: leptin actions in white adipose tissue

N Martínez-Sánchez - International journal of molecular sciences, 2020 - mdpi.com
Leptin is a hormone discovered almost 30 years ago with important implications in
metabolism. It is primarily produced by white adipose tissue (WAT) in proportion to the …

Crosstalk between obesity, diabetes, and alzheimer's disease: Introducing quercetin as an effective triple herbal medicine

S Ebrahimpour, M Zakeri, A Esmaeili - Ageing research reviews, 2020 - Elsevier
Obesity and diabetes are the most common metabolic disorders, which are strongly related
to Alzheimer's disease (AD) in aging. Diabetes and obesity can lead to the accumulation of …

Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects

G Milos, J Antel, LK Kaufmann, N Barth, A Koller… - Translational …, 2020 - nature.com
To examine the hypothesis that normalization of low circulating leptin levels in patients with
anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity …

Leptin: less is more

S Zhao, CM Kusminski, JK Elmquist, PE Scherer - Diabetes, 2020 - Am Diabetes Assoc
The successful use of leptin for the treatment of individuals with lipodystrophy and leptin
deficiency is well established. However, pharmacological approaches of leptin therapy for …

[HTML][HTML] Leptin as a key between obesity and cardiovascular disease

KW Kang, M Ok, SK Lee - Journal of Obesity & Metabolic Syndrome, 2020 - ncbi.nlm.nih.gov
Obesity increases the risk of cardiovascular disease through various influencing factors.
Leptin, which is predominantly secreted by adipose tissue, regulates satiety homeostasis …

Short-term ketogenic diet improves abdominal obesity in overweight/obese Chinese young females

Z Kong, S Sun, Q Shi, H Zhang, TK Tong… - Frontiers in Physiology, 2020 - frontiersin.org
The purpose of this study was to examine the effects of a short-term ketogenic diet (KD) on
body composition and cardiorespiratory fitness (CRF) in overweight/obese Chinese females …

Гормон лептин, его функции и значение в организме

Г Юлдашева, З Эргашева, Б Журабоев… - Re-health …, 2020 - cyberleninka.ru
У пациентов, страдающих ожирением и избыточным весом, гормональные изменения
влияют на их общее состояние здоровья. Избыток жира в организме может привести к …

Srebp-1c/Fgf21/Pgc-1α Axis regulated by leptin signaling in adipocytes—possible mechanism of caloric restriction-associated metabolic remodeling of white adipose …

M Kobayashi, S Uta, M Otsubo, Y Deguchi, R Tagawa… - Nutrients, 2020 - mdpi.com
Caloric restriction (CR) improves whole body metabolism, suppresses age-related
pathophysiology, and extends lifespan in rodents. Metabolic remodeling, including fatty acid …

Studies on characteristics and anti-diabetic and-nephritic effects of polysaccharides isolated from Paecilomyces hepiali fermentation mycelium in db/db mice

W Hu, J Wang, W Guo, Y Liu, Z Guo, Y Miao… - Carbohydrate …, 2020 - Elsevier
Type 2 diabetes mellitus plagues many people in China and the world, and its nephritis
complication is the leading cause of death for patients. Paecilomyces hepiali contained …

[HTML][HTML] Role of insulin, adenosine, and adipokine receptors in the foetoplacental vascular dysfunction in gestational diabetes mellitus

M Subiabre, R Villalobos-Labra, L Silva… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Gestational diabetes mellitus (GDM) is a disease of pregnancy associated with maternal and
foetal hyperglycaemia and altered foetoplacental vascular function. Human foetoplacental …