[HTML][HTML] A new positron emission tomography probe for orexin receptors neuroimaging

P Bai, S Bai, MS Placzek, X Lu, SA Fiedler, B Ntaganda… - Molecules, 2020 - mdpi.com
The orexin receptor (OX) is critically involved in motivation and sleep− wake regulation and
holds promising therapeutic potential in various mood disorders. To further investigate the …

Design and synthesis of chiral urea-derived iodoarenes and their assessment in the enantioselective dearomatizing cyclization of a naphthyl amide

MU Tariq, WJ Moran - Tetrahedron, 2020 - Elsevier
A novel family of urea-derived chiral iodoarenes was designed and synthesized for use in
enantioselective iodine (I/III) catalysis. Their preparation required the development of a …

Combination therapy

KDG Pfleger, E McCall, J Williams - US Patent 10,525,038, 2020 - Google Patents
The invention relates to pharmaceutical compositions comprising:(a) at least one
angiotensin receptor blocker or a pharmaceutically acceptable salt thereof, and (b) at least …