Sequence characterization and molecular modeling of clinically relevant variants of the SARS-CoV-2 main protease

TJ Cross, GR Takahashi, EM Diessner, MG Crosby… - Biochemistry, 2020 - ACS Publications
The SARS-CoV-2 main protease (M pro) is essential to viral replication and cleaves highly
specific substrate sequences, making it an obvious target for inhibitor design. However, as …

[HTML][HTML] The Droserasin 1 PSI: A Membrane-Interacting Antimicrobial Peptide from the Carnivorous Plant Drosera capensis

MA Sprague-Piercy, JC Bierma, MG Crosby… - Biomolecules, 2020 - mdpi.com
The Droserasins, aspartic proteases from the carnivorous plant Drosera capensis, contain a
100-residue plant-specific insert (PSI) that is post-translationally cleaved and independently …