Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …

Human pluripotent embryonic stem cells have two special features: self-renewal and
pluripotency. It is important to understand the properties of pluripotent stem cells and …

Expressed by cancer stem cells of various epithelial cell origins and hepatocellular
carcinoma (HCC), CD133 is an attractive therapeutic target for HCC. The marker CD133 is …

Abstract Prominin 1 (PROM1) is considered a biomarker for cancer stem cells, although its
biological role is unclear. Prominin 2 (PROM2) has also been associated with certain …

Axon regeneration is regulated by a neuron-intrinsic transcriptional program that is
suppressed during development but that can be reactivated following peripheral nerve …

In recent years, the deoxycytidine analogue gemcitabine (2′, 2′,-difluorodeoxycytidine)
has become the first-line chemotherapeutic agent for patients with pancreatic cancer …

Peripherin 2 (Prph2) is a photoreceptor-specific tetraspanin protein present in the outer
segment (OS) rims of rod and cone photoreceptors. It shares many common features with …

Prominins (proms) are transmembrane glycoproteins conserved throughout the animal
kingdom. They are associated with plasma membrane protrusions, such as primary cilia, as …

Digestive system cancers are the most frequent cancers worldwide and often associated
with poor prognosis because of their invasive and metastatic characteristics. Recent studies …

Melanoma is notoriously resistant to current cancer therapy. However, the chemoresistance
mechanism of melanoma remains unclear. The present study unveiled that chemotherapy …