A review of the tumour spectrum of germline succinate dehydrogenase gene mutations: Beyond phaeochromocytoma and paraganglioma
J MacFarlane, KC Seong, C Bisambar… - Clinical …, 2020 - Wiley Online Library
The citric acid cycle, also known as the Krebs cycle, plays an integral role in cellular
metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle …
metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle …
[HTML][HTML] The role of cancer-associated fibroblasts in renal cell carcinoma. An example of tumor modulation through tumor/non-tumor cell interactions
P Errarte, G Larrinaga, JI López - Journal of advanced research, 2020 - Elsevier
Cancer-associated fibroblasts (CAF) are a cellular compartment of the tumor
microenvironment (TME) with critical roles in tumor development. Fibroblast activation …
microenvironment (TME) with critical roles in tumor development. Fibroblast activation …
Noninvasive Fuhrman grading of clear cell renal cell carcinoma using computed tomography radiomic features and machine learning
Purpose To identify optimal classification methods for computed tomography (CT) radiomics-
based preoperative prediction of clear cell renal cell carcinoma (ccRCC) grade. Materials …
based preoperative prediction of clear cell renal cell carcinoma (ccRCC) grade. Materials …
Small renal mass surveillance: histology-specific growth rates in a biopsy-characterized cohort
A Finelli, DC Cheung, A Al-Matar, AJ Evans… - European urology, 2020 - Elsevier
Background Most reports of active surveillance (AS) of small renal masses (SRMs) lack
biopsy confirmation, and therefore include benign tumors and different subtypes of renal cell …
biopsy confirmation, and therefore include benign tumors and different subtypes of renal cell …
Report from the international society of urological pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: molecular pathology of …
Renal cell carcinoma (RCC) subtypes are increasingly being discerned via their molecular
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity
We recently proposed that an epithelial renal tumor “papillary renal neoplasm with reverse
polarity” represents a distinct entity. It constituted 4% of previously diagnosed papillary renal …
polarity” represents a distinct entity. It constituted 4% of previously diagnosed papillary renal …
Diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal oncocytomas and other benign renal lesions: a systematic review and meta-analysis
Purpose The primary objectives of this systematic review and meta-analysis were to
evaluate the diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal …
evaluate the diagnostic accuracy of 99mTc-sestamibi SPECT/CT for detecting renal …
Deep Learning Based on MRI for Differentiation of Low‐and High‐Grade in Low‐Stage Renal Cell Carcinoma
Background Pretreatment determination of renal cell carcinoma aggressiveness may help to
guide clinical decision‐making. Purpose To evaluate the efficacy of residual convolutional …
guide clinical decision‐making. Purpose To evaluate the efficacy of residual convolutional …
Targeted therapy for metastatic renal cell carcinoma
Background Several comparative randomised controlled trials (RCTs) have been performed
including combinations of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors …
including combinations of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors …
Extracellular vesicles enriched in hsa-miR-301a-3p and hsa-miR-1293 dynamics in clear cell renal cell carcinoma patients: potential biomarkers of metastatic disease
F Dias, AL Teixeira, I Nogueira, M Morais, J Maia… - Cancers, 2020 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most aggressive subtype of kidney cancer
and up to 40% of patients submitted to surgery with a curative intent will relapse. Thus, the …
and up to 40% of patients submitted to surgery with a curative intent will relapse. Thus, the …