[HTML][HTML] miRNAs: EBV mechanism for escaping host's immune response and supporting tumorigenesis

S Židovec Lepej, M Matulić, P Gršković, M Pavlica… - Pathogens, 2020 - mdpi.com
Epstein-Barr virus (EBV) or human herpesvirus 4 (HHV-4) is a ubiquitous human oncogenic
virus, and the first human virus found to express microRNAs (miRNAs). Its genome contains …

Non-coding RNAs in diffuse large B-cell lymphoma

Y Shi, D Ding, R Qu, Y Tang, S Hao - OncoTargets and therapy, 2020 - Taylor & Francis
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma
worldwide. The molecular mechanisms underlying DLBCL have not been fully elucidated …

EBV-miR-BART10-3p and EBV-miR-BART22 promote metastasis of EBV-associated gastric carcinoma by activating the canonical Wnt signaling pathway

M Dong, L Gong, J Chen, X Zhang, Y Zhang, D Hui… - Cellular Oncology, 2020 - Springer
Abstract Purpose Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC)
constitutes the largest subpopulation in EBV-associated tumors worldwide. To date, 44 …

[HTML][HTML] Loss of RBMS1 as a regulatory target of miR-106b influences cell growth, gap closing and colony forming in prostate carcinoma

JT Dankert, M Wiesehöfer, S Wach, ED Czyrnik… - Scientific Reports, 2020 - nature.com
Prostate carcinoma (PCa) is the second most commonly diagnosed cancer in males
worldwide. Among hereditary genetic mutations and nutrient factors, a link between the …

[HTML][HTML] The E3 ubiquitin ligase SIAH1 targets MyD88 for proteasomal degradation during dengue virus infection

AR Murphy Schafer, JL Smith, KM Pryke… - Frontiers in …, 2020 - frontiersin.org
The dengue virus presents a serious threat to human health globally and can cause severe,
even life-threatening, illness. Dengue virus (DENV) is endemic on all continents except …

Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2

J Wu, Y Xue, X Gao, Q Zhou - Nucleic acids research, 2020 - academic.oup.com
Abstract The Siah1 and Siah2 ubiquitin ligases are implicated in diverse biological
processes ranging from cellular stress responses, signaling to transcriptional regulation. A …

[HTML][HTML] EBV-mIR-BHRF1-1 targets p53 gene: Potential role in Epstein-Barr virus associated chronic lymphocytic leukemia

DM Xu, YL Kong, L Wang, HY Zhu, JZ Wu… - Cancer Research and …, 2020 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to investigate the prognostic impact of Epstein-Barr
virus (EBV)–microRNA (miRNA, miR)-BHRF1-1 with chronic lymphocytic leukemia (CLL) as …

Identification of microRNAs modulated by DNA hypomethylating drugs in extranodal NK/T-cell lymphoma

H Go, JY Jang, CW Kim, J Huh, PJ Kim… - Leukemia & …, 2020 - Taylor & Francis
To identify epigenetically silenced miRNAs and to investigate their influences on predictive
target oncogenes in extranodal natural killer/T-cell lymphoma (NKTCL). Decitabine …

[HTML][HTML] Differential expression analysis comparing EBV uninfected to infected human cell lines identifies induced non-micro small non-coding RNAs

LI Moss, VS Tompkins, WN Moss - Non-coding RNA Research, 2020 - Elsevier
Epstein–Barr virus (EBV) is a ubiquitous human herpes virus, which is implicated in cancer
and various autoimmune diseases. This study profiles non-micro small non-coding RNA …

Broadening Adenoviral Oncolysis in PDAC: Interrogation of Patient-Derived Organoids for personalized virotherapy and modulation of miRNA content to boost …

G Raimondi - 2020 - diposit.ub.edu
[eng] The general goal of this thesis has been to progress oncolytic adenovirus therapy for
PDAC, by the incorporation of novel preclinical models to test for patient-specific responses …