Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs

M Chinnappan, A Srivastava, N Amreddy, M Razaq… - Cancer letters, 2020 - Elsevier
Exosomes are small membranous vesicles implicated in intercellular signalling. Through
their uncanny ability to carry and deliver donor cellular cargo (biomolecules) to target cells …

[HTML][HTML] Extracellular vesicle-based therapeutics: Preclinical and clinical investigations

NL Klyachko, CJ Arzt, SM Li, OA Gololobova… - Pharmaceutics, 2020 - mdpi.com
Drug nanoformulations hold remarkable promise for the efficient delivery of therapeutics to a
disease site. Unfortunately, artificial nanocarriers, mostly liposomes and polymeric …

Inhibition of glioma cells' proliferation by doxorubicin-loaded exosomes via microfluidics

A Thakur, RK Sidu, H Zou, MK Alam… - International journal of …, 2020 - Taylor & Francis
Background Malignant glioma is a fatal brain cancer. Accumulated evidence has
demonstrated that exosomes can cross the blood–brain barrier (BBB), suggesting their …

[HTML][HTML] Recent advances in extracellular vesicles as drug delivery systems and their potential in precision medicine

B de Jong, ER Barros, JGJ Hoenderop, JP Rigalli - Pharmaceutics, 2020 - mdpi.com
Extracellular vesicles (EVs) are membrane-bilayered nanoparticles released by most cell
types. Recently, an enormous number of studies have been published on the potential of …

The role of exosomes in colorectal cancer disease progression and response to therapy

L Bracci, F Lozupone, I Parolini - Cytokine & growth factor reviews, 2020 - Elsevier
Colorectal cancer (CRC) is the second leading cause of cancer mortality in both men and
women worldwide. Survival of patients is significantly associated with disease stage at …

Segmentation techniques for early cancer detection in red blood cells with deep learning‐based classifier—a comparative approach

JS Shemona, AK Chellappan - IET Image Processing, 2020 - Wiley Online Library
Red Blood Corpuscles called Erythrocytes are the most important element in blood
composition which is mainly responsible in all living cells. To detect the cancer cell various …

[PDF][PDF] Comparative analysis of exosome markers and extracellular vesicles between colorectal cancer and cancer-associated normal colonic mucosa

Ł Zadka, A Piotrowska, A Opalińska… - Pol Arch Intern …, 2020 - scholar.archive.org
IntroductIon Exosomes are currently considered as the new biomarkers of colorectal cancer
(CRC). Tetraspanins (CD9, CD63) belong to the well‑known exosome markers, but can also …