Ibuprofen safety at the golden anniversary: are all NSAIDs the same? A narrative review

G Varrassi, JV Pergolizzi, P Dowling, A Paladini - Advances in therapy, 2020 - Springer
Ibuprofen first came to market about 50 years ago and rapidly moved to over-the-counter
(OTC) sales. In April 2019, the National Agency for the Safety of Medicines and Health …

[HTML][HTML] Host responses to mucosal biofilms in the lung and gut

JC Domingue, JL Drewes, CA Merlo, F Housseau… - Mucosal …, 2020 - Elsevier
The impact of the human microbiome on health and disease is of utmost importance and has
been studied intensively in recent years. Microbes promote immune system development …

Novel anti-inflammatory approaches for cystic fibrosis lung disease: Identification of molecular targets and design of innovative therapies

C Mitri, Z Xu, P Bardin, H Corvol, L Touqui… - Frontiers in …, 2020 - frontiersin.org
Cystic fibrosis (CF) is the most common genetic disorder among Caucasians, estimated to
affect more than 70,000 people in the world. Severe and persistent bronchial inflammation …

Airway redox homeostasis and inflammation gone awry: from molecular pathogenesis to emerging therapeutics in respiratory pathology

J Checa, JM Aran - International journal of molecular sciences, 2020 - mdpi.com
As aerobic organisms, we are continuously and throughout our lifetime subjected to an
oxidizing atmosphere and, most often, to environmental threats. The lung is the internal …

Role of cystic fibrosis bronchial epithelium in neutrophil chemotaxis

G Cabrini, A Rimessi, M Borgatti, I Lampronti… - Frontiers in …, 2020 - frontiersin.org
A hallmark of cystic fibrosis (CF) chronic respiratory disease is an extensive neutrophil
infiltrate in the mucosa filling the bronchial lumen, starting early in life for CF infants. The …

Kids, difficult asthma and fungus

A Bush - Journal of Fungi, 2020 - mdpi.com
Fungi have many potential roles in paediatric asthma, predominantly by being a source of
allergens (severe asthma with fungal sensitization, SAFS), and also directly damaging the …

Omega‐3 fatty acid supplementation for cystic fibrosis

H Watson, C Stackhouse - Cochrane Database of Systematic …, 2020 - cochranelibrary.com
Background Studies suggest that a diet rich in omega‐3 essential fatty acids may have
beneficial anti‐inflammatory effects for chronic conditions such as cystic fibrosis. This is an …

An in vitro model for assessing drug transport in cystic fibrosis treatment: Characterisation of the CuFi-1 cell line

Z Sheikh, P Bradbury, M Pozzoli, PM Young… - European Journal of …, 2020 - Elsevier
Cystic fibrosis (CF) is a disease that most commonly affects the lungs and is characterized
by mucus retention and a continuous cycle of bacterial infection and inflammation. Current …

Cystic fibrosis–Ten promising therapeutic approaches in the current era of care

R Somayaji, DP Nichols, SC Bell - Expert opinion on …, 2020 - Taylor & Francis
Introduction Cystic fibrosis (CF) is a genetic disease affecting multiple organ systems.
Research and innovations in novel therapeutic agents and health care delivery have …

Consenso chileno para la atención integral de niños y adultos con fibrosis quística

ML Boza, J Melo, S Barja, E Codner… - Revista chilena de …, 2020 - SciELO Chile
Resumen La Fibrosis Quística (FQ) es la enfermedad hereditaria de pronóstico reservado
más frecuente en raza blanca. Desde el año 2003, Chile inicia un Programa Nacional de …