Dynamic bioinks to advance bioprinting

FLC Morgan, L Moroni, MB Baker - Advanced healthcare …, 2020 - Wiley Online Library
The development of bioinks for bioprinting of cell‐laden constructs remains a challenge for
tissue engineering, despite vigorous investigation. Hydrogels to be used as bioinks must …

Recent progress in design and preparation of glucose-responsive insulin delivery systems

D Shen, H Yu, L Wang, A Khan, F Haq, X Chen… - Journal of Controlled …, 2020 - Elsevier
Diabetes, as a global threat nowadays, causes the wide usage of exogenous insulin.
Subcutaneous injection is the traditional insulin administration in the diabetes treatments …

Composition-engineered metal–organic framework-based microneedles for glucose-mediated transdermal insulin delivery

XX Yang, P Feng, J Cao, W Liu… - ACS applied materials & …, 2020 - ACS Publications
Elaborately designed glucose-responsive insulin-delivery systems are highly desirable for
the treatment of diabetes because it can secrete insulin depending on blood glucose levels …

Responsive boron biomaterials and their biomedical applications

W Chen, X Zhen, W Wu, X Jiang - Science China Chemistry, 2020 - Springer
Due to the formation of dynamic boronate ester bonds between phenylboronic acid (PBA)
and 1, 2-and 1, 3-diols, PBA-containing biomaterials show increasing applications in …

Synthesis and characterization of phenylboronic acid-containing polymer for glucose-triggered drug delivery+

G Cui, K Zhao, K You, Z Gao, T Kakuchi… - … and Technology of …, 2020 - Taylor & Francis
ABSTRACT Thermo-, pH-and glucose-responsive polymeric nanoparticles are of great
interest in developing a self-regulated drug delivery system. The novel core-shell …

Polymer-supported Lewis acids and bases: Synthesis and applications

U Yolsal, TAR Horton, M Wang, MP Shaver - Progress in Polymer Science, 2020 - Elsevier
In the past decade the synthesis of novel stimuli-responsive materials has been driven by
the pursuit of new applications and, more recently, sustainable and reusable systems. Of …

Boronic acid and diol-containing polymers: how to choose the correct couple to form “strong” hydrogels at physiological pH

T Figueiredo, V Cosenza, Y Ogawa, I Jeacomine… - Soft Matter, 2020 - pubs.rsc.org
Dynamic covalent hydrogels crosslinked by boronate ester bonds are promising materials
for biomedical applications. However, little is known about the impact of the crosslink …

Glycopolypeptide nanocarriers based on dynamic covalent bonds for glucose dual-responsiveness and self-regulated release of insulin in diabetic rats

Y Wang, Y Fan, M Zhang, W Zhou, Z Chai… - …, 2020 - ACS Publications
An intelligent carrier system is based on fast glucose response mechanism to regulate the
insulin release. Here, glucose dual-responsive nanoparticles were quickly and efficiently …

Neutral pH monosaccharide receptor based on boronic acid decorated poly (2-hydroxyethyl methacrylate): Spectral Methods for determination of glucose-binding and …

B Dehghani, MS Hosseini, M Salami-Kalajahi - Microchemical Journal, 2020 - Elsevier
Herein, a glucose-responsive polymer featuring boronic acid has been synthesized that
operates under physiological conditions. Phenylboronic acid-containing polymer has been …

In situ‐forming glucose‐responsive hydrogel from hyaluronic acid modified with a boronic acid derivative

E Holz, K Rajagopal - Macromolecular Chemistry and Physics, 2020 - Wiley Online Library
Hydrogels are a promising class of biomaterials for sustained drug release applications. The
use of covalently cross‐linked hydrogels for drug delivery applications may be limited due to …