The implausibility of neonatal opioid toxicity from breastfeeding

J Zipursky, DN Juurlink - Clinical Pharmacology & Therapeutics, 2020 - Wiley Online Library
The belief that newborns can develop opioid toxicity from breastfeeding is widely held but
supported by very little data. Based largely on a single, highly publicized case report (the …

A preterm physiologically based pharmacokinetic model. Part I: physiological parameters and model building

K Abduljalil, X Pan, A Pansari, M Jamei… - Clinical …, 2020 - Springer
Background Developmental physiology can alter pharmacotherapy in preterm populations.
Because of ethical and clinical constraints in studying this vulnerable age group …

Personalized pediatric anesthesia and pain management: problem-based review

S Packiasabapathy, V Rangasamy, N Horn… - …, 2020 - Taylor & Francis
Pharmacogenetics, the genetic influence on the interpersonal variability in drug response,
has enabled tailored pharmacotherapy and emerging 'personalized medicine.'Although …

The influence of CYP2D6 metabolizer status on the control of emesis by ondansetron in pediatric patients undergoing hematopoietic stem cell transplantation

A Edwards - 2020 - search.proquest.com
Chemotherapy induced nausea and vomiting (CINV) is an adverse outcome commonly
experienced by patients receiving antineoplastic agents prior to hemopoietic stem cell …

Population Pharmacokinetic Modeling and Genetic Association Analysis in Infants with Neonatal Abstinence Syndrome Receiving Morphine Or Clonidine

F Tang - 2020 - uknowledge.uky.edu
Neonatal abstinence syndrome, or NAS, is a postnatal opioid withdrawal syndrome
occurring in 55% to 94% of neonates as a result of in utero exposure to opioids. It has …