Androgens are effective bronchodilators with anti-inflammatory properties: A potential alternative for asthma therapy
LM Montaño, E Flores-Soto, B Sommer… - Steroids, 2020 - Elsevier
Abstract Changes in plasma androgen levels in asthmatic men may be linked to asthma
severity, seemingly acting through nongenomic and genomic effects. Nongenomic effects …
severity, seemingly acting through nongenomic and genomic effects. Nongenomic effects …
[HTML][HTML] Sex‐specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry
Background Women are more susceptible than men to several forms of pulmonary
hypertension, but have better survival. Sparse data are available on chronic thromboembolic …
hypertension, but have better survival. Sparse data are available on chronic thromboembolic …
Sex-specific stress response and HMGB1 release in pulmonary endothelial cells
M Zemskova, S Kurdyukov, J James, N McClain… - PLoS …, 2020 - journals.plos.org
Women are known to be associated with a higher susceptibility to pulmonary arterial
hypertension (PAH). In contrast, male PAH patients have a worse survival prognosis. In this …
hypertension (PAH). In contrast, male PAH patients have a worse survival prognosis. In this …
Targeted drugs for treatment of pulmonary arterial hypertension: past, present, and future perspectives
W Zheng, Z Wang, X Jiang, Q Zhao… - Journal of Medicinal …, 2020 - ACS Publications
Pulmonary arterial hypertension (PAH) is a devastating disease that can lead to right
ventricular failure and premature death. Although approved drugs have been shown to be …
ventricular failure and premature death. Although approved drugs have been shown to be …
Blueberry extract decreases oxidative stress and improves functional parameters in lungs from rats with pulmonary arterial hypertension
P Türck, S Fraga, I Salvador, C Campos-Carraro… - Nutrition, 2020 - Elsevier
Objectives Pulmonary arterial hypertension (PAH) is a condition characterized by an
increased resistance of pulmonary vasculature, culminating in an increase in pulmonary …
increased resistance of pulmonary vasculature, culminating in an increase in pulmonary …
Quantitative 129Xe MRI detects early impairment of gas-exchange in a rat model of pulmonary hypertension
Hyperpolarized 129Xe magnetic resonance imaging (MRI) is capable of regional mapping
of pulmonary gas-exchange and has found application in a wide range of pulmonary …
of pulmonary gas-exchange and has found application in a wide range of pulmonary …
Estrogen administration reduces the risk of pulmonary arterial hypertension by modulating the miR-133a signaling pathways in rats
S Zhou, K Zhu, Y Du, H Jiang, M Li, P Wu, A Xu, X Ding… - Gene Therapy, 2020 - nature.com
We aimed to investigate how estrogen (ES) is implicated in the pathogenesis of pulmonary
arterial hypertension (PAH) potentially by reducing the extent of vascular remodeling in …
arterial hypertension (PAH) potentially by reducing the extent of vascular remodeling in …
Spontaneous pulmonary hypertension associated with systemic sclerosis in P‐selectin glycoprotein ligand 1–deficient mice
R González‐Tajuelo… - Arthritis & …, 2020 - Wiley Online Library
Objective Pulmonary arterial hypertension (PAH), one of the major complications of systemic
sclerosis (SSc), is a rare disease with unknown etiopathogenesis and noncurative …
sclerosis (SSc), is a rare disease with unknown etiopathogenesis and noncurative …
Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary …
R Hashimoto, GM Lanier, V Dhagia… - … of Physiology-Lung …, 2020 - journals.physiology.org
Pulmonary hypertension (PH) is a multicellular and progressive disease with a high mortality
rate. Among many cell types, hematopoietic stem cells (HSCs) are incriminated in the …
rate. Among many cell types, hematopoietic stem cells (HSCs) are incriminated in the …
NFU1, Iron-sulfur biogenesis, and pulmonary arterial hypertension: a (metabolic) shift in our thinking
MK Culley, D Perk, SY Chan - American Journal of Respiratory Cell …, 2020 - atsjournals.org
Pulmonary hypertension (PH) is a progressive, enigmatic disease of the lung vasculature
that is clinically defined by elevated mean pulmonary arterial pressure and pulmonary …
that is clinically defined by elevated mean pulmonary arterial pressure and pulmonary …