[HTML][HTML] Drug therapy in obesity: a review of current and emerging treatments
DM Williams, A Nawaz, M Evans - Diabetes Therapy, 2020 - Springer
Whilst the prevalence of obesity continues to increase at an alarming rate worldwide, the
personal and economic burden of obesity-related complications becomes ever more …
personal and economic burden of obesity-related complications becomes ever more …
Anti-diabetic drugs recent approaches and advancements
J Dowarah, VP Singh - Bioorganic & medicinal chemistry, 2020 - Elsevier
Diabetes is one of the major diseases worldwide and is the third leading cause of death in
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …
Obesity: scope, lifestyle interventions, and medical management
BJ McCafferty, JO Hill, AJ Gunn - Techniques in vascular and interventional …, 2020 - Elsevier
Obesity is a public health epidemic in the United States, with implications for patients across
many organ systems. Despite improvements in understanding the pathophysiology and …
many organ systems. Despite improvements in understanding the pathophysiology and …
Current and emerging therapies for managing hyperphagia and obesity in Prader‐Willi syndrome: A narrative review
In early childhood, individuals with Prader‐Willi syndrome (PWS) experience excess weight
gain and severe hyperphagia with food compulsivity, which often leads to early onset morbid …
gain and severe hyperphagia with food compulsivity, which often leads to early onset morbid …
GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats
SM Fortin, RK Lipsky, R Lhamo, J Chen… - Science translational …, 2020 - science.org
The glucagon-like peptide-1 receptor (GLP-1R) agonist liraglutide is approved for the
treatment of obesity; however, there is still much to be learned regarding the neuronal sites …
treatment of obesity; however, there is still much to be learned regarding the neuronal sites …
Liraglutide attenuates renal tubular ectopic lipid deposition in rats with diabetic nephropathy by inhibiting lipid synthesis and promoting lipolysis
Liraglutide is a new hypoglycemic drug. The previous studies have shown that liraglutide
can improve the renal outcomes of patients with type 2 diabetes. Recently, it was approved …
can improve the renal outcomes of patients with type 2 diabetes. Recently, it was approved …
An evaluation of liraglutide including its efficacy and safety for the treatment of obesity
CH Lin, L Shao, YM Zhang, YJ Tu, Y Zhang… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The prevalence of obesity is increasing worldwide and associated conditions,
particularly type 2 diabetes mellitus (T2DM), also show increasing prevalence. Lifestyle …
particularly type 2 diabetes mellitus (T2DM), also show increasing prevalence. Lifestyle …
[HTML][HTML] Effect of weight loss medications on hepatic steatosis and steatohepatitis: a systematic review
CS Pan, TL Stanley - Frontiers in Endocrinology, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a common comorbidity in individuals with
obesity. Although multiple pharmacotherapeutics are in development, currently there are …
obesity. Although multiple pharmacotherapeutics are in development, currently there are …
Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates
PJ Knerr, SA Mowery, B Finan, D Perez-Tilve… - Peptides, 2020 - Elsevier
The continued global growth in the prevalence of obesity coupled with the limited number of
efficacious and safe treatment options elevates the importance of innovative pharmaceutical …
efficacious and safe treatment options elevates the importance of innovative pharmaceutical …
[HTML][HTML] Metabolic surgery to treat obesity in diabetic kidney disease, chronic kidney disease, and end-stage kidney disease; what are the unanswered questions?
Obesity is a major factor in contemporary clinical practice in nephrology. Obesity accelerates
the progression of both diabetic and non-diabetic chronic kidney disease and, in renal …
the progression of both diabetic and non-diabetic chronic kidney disease and, in renal …